Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parE_1-relB/-
Location 1851543..1851937 Replicon chromosome
Accession NZ_CP087677
Organism Xylella taiwanensis strain PLS15A

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag LPH39_RS07425 Protein ID WP_200866186.1
Coordinates 1851543..1851746 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Z9JJI0
Locus tag LPH39_RS07430 Protein ID WP_038270756.1
Coordinates 1851743..1851937 (-) Length 65 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH39_RS07405 (LPH39_07405) 1846557..1846697 + 141 WP_160165149.1 hypothetical protein -
LPH39_RS07410 (LPH39_07410) 1847084..1848094 - 1011 WP_038270757.1 serine protease -
LPH39_RS07415 (LPH39_07415) 1849330..1850721 + 1392 WP_051482280.1 right-handed parallel beta-helix repeat-containing protein -
LPH39_RS07420 (LPH39_07420) 1850794..1851456 - 663 WP_268746643.1 recombinase family protein -
LPH39_RS07425 (LPH39_07425) 1851543..1851746 - 204 WP_200866186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LPH39_RS07430 (LPH39_07430) 1851743..1851937 - 195 WP_038270756.1 hypothetical protein Antitoxin
LPH39_RS07435 (LPH39_07435) 1852181..1852576 + 396 WP_230428271.1 DUF4158 domain-containing protein -
LPH39_RS07440 (LPH39_07440) 1852705..1853085 + 381 WP_038270750.1 hypothetical protein -
LPH39_RS07445 (LPH39_07445) 1853219..1853302 + 84 Protein_1469 type II toxin-antitoxin system RelE/ParE family toxin -
LPH39_RS07450 (LPH39_07450) 1853414..1853695 + 282 WP_038270748.1 XRE family transcriptional regulator -
LPH39_RS07455 (LPH39_07455) 1853965..1855094 - 1130 Protein_1471 DUF5710 domain-containing protein -
LPH39_RS07460 (LPH39_07460) 1855270..1856107 + 838 Protein_1472 VirB8/TrbF family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-61)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 68 a.a.        Molecular weight: 7625.95 Da        Isoelectric Point: 11.2308

>T225962 WP_200866186.1 NZ_CP087677:c1851746-1851543 [Xylella taiwanensis]
MTLPLHWRTSARDDLASLIRFIAYENPLTARRMKVLIEASVLLASAHPYMFRPGRVPGTREIVAHPN

Download         Length: 204 bp

>T225962 NZ_CP121632:3182684-3183073 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7289.11 Da        Isoelectric Point: 4.5007

>AT225962 WP_038270756.1 NZ_CP087677:c1851937-1851743 [Xylella taiwanensis]
MKTTPLDPIISEFATEEQAASYDRWFRAKVQASLDDSRPSVPHDQVMAEMDAIIAEAEQHRKQT

Download         Length: 195 bp

>AT225962 NZ_CP121632:3182420-3182677 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB Z9JJI0

References