Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1911215..1911360 Replicon chromosome
Accession NZ_CP087669
Organism Klebsiella pneumoniae strain KP53

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1911251..1911353 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1911215..1911360 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOM31_RS09445 1906345..1908405 + 2061 WP_004151449.1 oligopeptidase B -
LOM31_RS09450 1908409..1909068 - 660 WP_032425085.1 exodeoxyribonuclease X -
LOM31_RS09455 1909147..1909377 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LOM31_RS09460 1909490..1909864 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LOM31_RS09465 1909868..1910737 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LOM31_RS09470 1910754..1911092 + 339 WP_016529031.1 YebY family protein -
- 1911215..1911360 - 146 - - Antitoxin
- 1911251..1911353 + 103 - - Toxin
LOM31_RS09475 1911728..1911871 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LOM31_RS09480 1911976..1912944 - 969 WP_004151446.1 VirK/YbjX family protein -
LOM31_RS09485 1913101..1913754 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LOM31_RS09490 1913751..1913942 - 192 WP_002911395.1 YebW family protein -
LOM31_RS09495 1914040..1914279 - 240 WP_002911393.1 YebV family protein -
LOM31_RS09500 1914395..1915828 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225915 NZ_CP087669:1911251-1911353 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225915 NZ_CP087669:c1911360-1911215 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References