Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1999358..1999503 Replicon chromosome
Accession NZ_CP087663
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD01845

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1999394..1999496 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1999358..1999503 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMH56_RS09740 (LMH56_09740) 1994488..1996548 + 2061 WP_004151449.1 oligopeptidase B -
LMH56_RS09745 (LMH56_09745) 1996552..1997211 - 660 WP_002911407.1 exodeoxyribonuclease X -
LMH56_RS09750 (LMH56_09750) 1997290..1997520 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LMH56_RS09755 (LMH56_09755) 1997633..1998007 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LMH56_RS09760 (LMH56_09760) 1998011..1998880 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LMH56_RS09765 (LMH56_09765) 1998897..1999235 + 339 WP_002911404.1 YebY family protein -
- 1999358..1999503 - 146 - - Antitoxin
- 1999394..1999496 + 103 - - Toxin
LMH56_RS09770 (LMH56_09770) 1999871..2000014 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LMH56_RS09775 (LMH56_09775) 2000119..2001087 - 969 WP_004151446.1 VirK/YbjX family protein -
LMH56_RS09780 (LMH56_09780) 2001244..2001897 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LMH56_RS09785 (LMH56_09785) 2001894..2002085 - 192 WP_002911395.1 YebW family protein -
LMH56_RS09790 (LMH56_09790) 2002183..2002422 - 240 WP_002911393.1 YebV family protein -
LMH56_RS09795 (LMH56_09795) 2002538..2003971 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225888 NZ_CP087663:1999394-1999496 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225888 NZ_CP087663:c1999503-1999358 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References