Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2055974..2056119 Replicon chromosome
Accession NZ_CP087657
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD01635

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2056010..2056112 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2055974..2056119 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMH51_RS10120 (LMH51_10120) 2051104..2053164 + 2061 WP_004151449.1 oligopeptidase B -
LMH51_RS10125 (LMH51_10125) 2053168..2053827 - 660 WP_002911407.1 exodeoxyribonuclease X -
LMH51_RS10130 (LMH51_10130) 2053906..2054136 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LMH51_RS10135 (LMH51_10135) 2054249..2054623 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LMH51_RS10140 (LMH51_10140) 2054627..2055496 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LMH51_RS10145 (LMH51_10145) 2055513..2055851 + 339 WP_002911404.1 YebY family protein -
- 2055974..2056119 - 146 - - Antitoxin
- 2056010..2056112 + 103 - - Toxin
LMH51_RS10150 (LMH51_10150) 2056487..2056630 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LMH51_RS10155 (LMH51_10155) 2056735..2057703 - 969 WP_004151446.1 VirK/YbjX family protein -
LMH51_RS10160 (LMH51_10160) 2057860..2058513 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LMH51_RS10165 (LMH51_10165) 2058510..2058701 - 192 WP_002911395.1 YebW family protein -
LMH51_RS10170 (LMH51_10170) 2058799..2059038 - 240 WP_002911393.1 YebV family protein -
LMH51_RS10175 (LMH51_10175) 2059154..2060587 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225863 NZ_CP087657:2056010-2056112 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225863 NZ_CP087657:c2056119-2055974 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References