Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013566..2013711 Replicon chromosome
Accession NZ_CP087651
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD01653

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013602..2013704 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013566..2013711 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL272_RS09815 (LL272_09815) 2008696..2010756 + 2061 WP_004151449.1 oligopeptidase B -
LL272_RS09820 (LL272_09820) 2010760..2011419 - 660 WP_002911407.1 exodeoxyribonuclease X -
LL272_RS09825 (LL272_09825) 2011498..2011728 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LL272_RS09830 (LL272_09830) 2011841..2012215 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LL272_RS09835 (LL272_09835) 2012219..2013088 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LL272_RS09840 (LL272_09840) 2013105..2013443 + 339 WP_002911404.1 YebY family protein -
- 2013566..2013711 - 146 - - Antitoxin
- 2013602..2013704 + 103 - - Toxin
LL272_RS09845 (LL272_09845) 2014079..2014222 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LL272_RS09850 (LL272_09850) 2014327..2015295 - 969 WP_004151446.1 VirK/YbjX family protein -
LL272_RS09855 (LL272_09855) 2015452..2016105 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LL272_RS09860 (LL272_09860) 2016102..2016293 - 192 WP_002911395.1 YebW family protein -
LL272_RS09865 (LL272_09865) 2016391..2016630 - 240 WP_002911393.1 YebV family protein -
LL272_RS09870 (LL272_09870) 2016746..2018179 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225836 NZ_CP087651:2013602-2013704 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225836 NZ_CP087651:c2013711-2013566 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References