Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011891..2012036 Replicon chromosome
Accession NZ_CP087639
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD02391

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011927..2012029 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011891..2012036 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMH57_RS09860 (LMH57_09860) 2007021..2009081 + 2061 WP_004151449.1 oligopeptidase B -
LMH57_RS09865 (LMH57_09865) 2009085..2009744 - 660 WP_002911407.1 exodeoxyribonuclease X -
LMH57_RS09870 (LMH57_09870) 2009823..2010053 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LMH57_RS09875 (LMH57_09875) 2010166..2010540 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LMH57_RS09880 (LMH57_09880) 2010544..2011413 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LMH57_RS09885 (LMH57_09885) 2011430..2011768 + 339 WP_002911404.1 YebY family protein -
- 2011891..2012036 - 146 - - Antitoxin
- 2011927..2012029 + 103 - - Toxin
LMH57_RS09890 (LMH57_09890) 2012404..2012547 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LMH57_RS09895 (LMH57_09895) 2012652..2013620 - 969 WP_004151446.1 VirK/YbjX family protein -
LMH57_RS09900 (LMH57_09900) 2013777..2014430 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LMH57_RS09905 (LMH57_09905) 2014427..2014618 - 192 WP_002911395.1 YebW family protein -
LMH57_RS09910 (LMH57_09910) 2014716..2014955 - 240 WP_002911393.1 YebV family protein -
LMH57_RS09915 (LMH57_09915) 2015071..2016504 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225785 NZ_CP087639:2011927-2012029 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225785 NZ_CP087639:c2012036-2011891 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References