Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012010..2012155 Replicon chromosome
Accession NZ_CP087623
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD02280

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012046..2012148 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012010..2012155 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMH50_RS09835 (LMH50_09835) 2007140..2009200 + 2061 WP_004151449.1 oligopeptidase B -
LMH50_RS09840 (LMH50_09840) 2009204..2009863 - 660 WP_002911407.1 exodeoxyribonuclease X -
LMH50_RS09845 (LMH50_09845) 2009942..2010172 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LMH50_RS09850 (LMH50_09850) 2010285..2010659 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LMH50_RS09855 (LMH50_09855) 2010663..2011532 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LMH50_RS09860 (LMH50_09860) 2011549..2011887 + 339 WP_002911404.1 YebY family protein -
- 2012010..2012155 - 146 - - Antitoxin
- 2012046..2012148 + 103 - - Toxin
LMH50_RS09865 (LMH50_09865) 2012523..2012666 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LMH50_RS09870 (LMH50_09870) 2012771..2013739 - 969 WP_004151446.1 VirK/YbjX family protein -
LMH50_RS09875 (LMH50_09875) 2013896..2014549 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LMH50_RS09880 (LMH50_09880) 2014546..2014737 - 192 WP_002911395.1 YebW family protein -
LMH50_RS09885 (LMH50_09885) 2014835..2015074 - 240 WP_002911393.1 YebV family protein -
LMH50_RS09890 (LMH50_09890) 2015190..2016623 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225706 NZ_CP087623:2012046-2012148 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225706 NZ_CP087623:c2012155-2012010 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References