Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1938833..1938978 Replicon chromosome
Accession NZ_CP087618
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD02162

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1938869..1938971 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1938833..1938978 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMH58_RS09255 1933963..1936023 + 2061 WP_004151449.1 oligopeptidase B -
LMH58_RS09260 1936027..1936686 - 660 WP_020324964.1 exodeoxyribonuclease X -
LMH58_RS09265 1936765..1936995 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LMH58_RS09270 1937108..1937482 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LMH58_RS09275 1937486..1938355 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
LMH58_RS09280 1938372..1938710 + 339 WP_002911404.1 YebY family protein -
- 1938833..1938978 - 146 - - Antitoxin
- 1938869..1938971 + 103 - - Toxin
LMH58_RS09285 1939347..1939490 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LMH58_RS09290 1939595..1940563 - 969 WP_004151446.1 VirK/YbjX family protein -
LMH58_RS09295 1940720..1941373 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LMH58_RS09300 1941370..1941561 - 192 WP_002911395.1 YebW family protein -
LMH58_RS09305 1941659..1941898 - 240 WP_002911393.1 YebV family protein -
LMH58_RS09310 1942014..1943447 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225683 NZ_CP087618:1938869-1938971 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225683 NZ_CP087618:c1938978-1938833 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References