Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1974269..1974414 Replicon chromosome
Accession NZ_CP087611
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD02172

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1974305..1974407 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1974269..1974414 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMH59_RS09450 1969399..1971459 + 2061 WP_004151449.1 oligopeptidase B -
LMH59_RS09455 1971463..1972122 - 660 WP_020324964.1 exodeoxyribonuclease X -
LMH59_RS09460 1972201..1972431 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LMH59_RS09465 1972544..1972918 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LMH59_RS09470 1972922..1973791 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
LMH59_RS09475 1973808..1974146 + 339 WP_002911404.1 YebY family protein -
- 1974269..1974414 - 146 - - Antitoxin
- 1974305..1974407 + 103 - - Toxin
LMH59_RS09480 1974783..1974926 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LMH59_RS09485 1975031..1975999 - 969 WP_004151446.1 VirK/YbjX family protein -
LMH59_RS09490 1976156..1976809 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LMH59_RS09495 1976806..1976997 - 192 WP_002911395.1 YebW family protein -
LMH59_RS09500 1977095..1977334 - 240 WP_002911393.1 YebV family protein -
LMH59_RS09505 1977450..1978883 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225655 NZ_CP087611:1974305-1974407 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225655 NZ_CP087611:c1974414-1974269 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References