Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1865156..1865669 Replicon chromosome
Accession NZ_CP087590
Organism Vibrio sp. VB16

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag IUZ65_RS08490 Protein ID WP_195703321.1
Coordinates 1865156..1865422 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IUZ65_RS08495 Protein ID WP_195703322.1
Coordinates 1865415..1865669 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUZ65_RS08470 (IUZ65_008470) 1860536..1860694 - 159 WP_195703317.1 hypothetical protein -
IUZ65_RS08475 (IUZ65_008475) 1861252..1862628 + 1377 WP_195703318.1 sodium:alanine symporter family protein -
IUZ65_RS08480 (IUZ65_008480) 1862845..1863495 - 651 WP_195703319.1 LysE family translocator -
IUZ65_RS08485 (IUZ65_008485) 1863615..1865096 + 1482 WP_195703320.1 carboxypeptidase M32 -
IUZ65_RS08490 (IUZ65_008490) 1865156..1865422 - 267 WP_195703321.1 Txe/YoeB family addiction module toxin Toxin
IUZ65_RS08495 (IUZ65_008495) 1865415..1865669 - 255 WP_195703322.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IUZ65_RS08500 (IUZ65_008500) 1865885..1866144 + 260 Protein_1652 carboxypeptidase M32 -
IUZ65_RS08505 (IUZ65_008505) 1866296..1866943 - 648 WP_195703323.1 class I SAM-dependent methyltransferase -
IUZ65_RS08510 (IUZ65_008510) 1867084..1867983 + 900 WP_195703324.1 LysR family transcriptional regulator -
IUZ65_RS08515 (IUZ65_008515) 1868128..1868292 + 165 Protein_1655 carboxypeptidase M32 -
IUZ65_RS08520 (IUZ65_008520) 1868335..1868664 - 330 WP_195703325.1 type II toxin-antitoxin system RelE/ParE family toxin -
IUZ65_RS08525 (IUZ65_008525) 1868668..1868943 - 276 WP_195703326.1 hypothetical protein -
IUZ65_RS08530 (IUZ65_008530) 1869489..1870409 + 921 WP_195703327.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10487.92 Da        Isoelectric Point: 9.4082

>T225602 WP_195703321.1 NZ_CP087590:c1865422-1865156 [Vibrio sp. VB16]
MSNQRLLSWTDEAWGSYLYWQTQDKKTLKRINKLINDVKRTPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYAVDGETMT
IISCRYHY

Download         Length: 267 bp

>T225602 NZ_CP121204:c2102309-2102133 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9509.71 Da        Isoelectric Point: 5.1007

>AT225602 WP_195703322.1 NZ_CP087590:c1865669-1865415 [Vibrio sp. VB16]
MRIVSFTEARNGLKAVLDSVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPKNAEHLNRSIAQYRAGKVEARE
LIDE

Download         Length: 255 bp

>AT225602 NZ_CP121204:2102010-2102065 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References