Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2893650..2894158 Replicon chromosome
Accession NZ_CP087584
Organism Providencia rettgeri strain L1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag LMY39_RS13070 Protein ID WP_210846854.1
Coordinates 2893850..2894158 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag LMY39_RS13065 Protein ID WP_230233553.1
Coordinates 2893650..2893850 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMY39_RS13045 (LMY39_13045) 2889079..2889381 + 303 WP_042844270.1 flagellar biosynthesis anti-sigma factor FlgM -
LMY39_RS13050 (LMY39_13050) 2889391..2889831 + 441 WP_042844271.1 flagellar export chaperone FlgN -
LMY39_RS13055 (LMY39_13055) 2890202..2892301 - 2100 WP_042844272.1 flagellar biosynthesis protein FlhA -
LMY39_RS13060 (LMY39_13060) 2892294..2893445 - 1152 WP_042844273.1 flagellar biosynthesis protein FlhB -
LMY39_RS13065 (LMY39_13065) 2893650..2893850 + 201 WP_230233553.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
LMY39_RS13070 (LMY39_13070) 2893850..2894158 + 309 WP_210846854.1 CcdB family protein Toxin
LMY39_RS13075 (LMY39_13075) 2894174..2894731 + 558 WP_071547928.1 hypothetical protein -
LMY39_RS13080 (LMY39_13080) 2894752..2895051 - 300 WP_042844276.1 helix-turn-helix transcriptional regulator -
LMY39_RS13085 (LMY39_13085) 2895268..2895906 - 639 WP_042844277.1 protein phosphatase CheZ -
LMY39_RS13090 (LMY39_13090) 2895931..2896323 - 393 WP_034782834.1 chemotaxis response regulator CheY -
LMY39_RS13095 (LMY39_13095) 2896363..2897430 - 1068 WP_042844278.1 chemotaxis response regulator protein-glutamate methylesterase -
LMY39_RS13100 (LMY39_13100) 2897430..2898266 - 837 WP_042844279.1 CheR family methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(1-66)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11685.77 Da        Isoelectric Point: 6.9450

>T225596 WP_210846854.1 NZ_CP087584:2893850-2894158 [Providencia rettgeri]
MQYCLYQNRENTVKHPYLLDIQSNIIDILNTLLVIPLFDSRLVKKPLPTCLNPQLFSNGQVFVLMTHQMACVPHSLLGKE
IVDLNCQHNTIKHAIDLLIDGF

Download         Length: 309 bp

>T225596 NZ_CP121201:c754610-753765 [Streptococcus pluranimalium]
ATGAACAAAGCTAAATTAACAGCACTCTGTCATAAAATATCAAAGAATACTGGTTTAACCTTTAATTCCGTCATGACCTA
TTACTTCCTAGAAGTCATTTTGAAAAAATTAAGTCAAAGTTCTTATTCAAATCACTATATCTTCAAAGGAGGATTCCTAC
TTTCGAATGTCATCGGAGTTGAATCTCGTAGCACTGTTGATATTGACTTTTTATTCCATCAAATAACACTCTCAGAAGAA
ACTGTTAAACAGCAACTCAAGGAAATTTTAGCAGATTCCGAAGAAGGTATATCTTTTGTGATTCAATCAATCACAGCTAT
TAAAGAAAGTGATGACTATGGTGGCTATCGAGCAACAATTTCGTGCCAACTTGAGAATATTAAACAAGTTATCCATTTGG
ATATTGCGACAGGTGATGTTGTAACTCCTCAGCCGATTACATACGACTATAAAGCTATTTTTGATGAAGACAATTTTCCA
ATCATTGCTTATACAATTGAAACAATTCTAGCTGAAAAACTTCAAACCATCTATTCACGTAACTTCTTGAACAGTAGAAG
CAAAGATTTTTACGATGTTTATATTCTTTCCAAACTGAAGAAAGAAGACATTGACTTCATTCAGTTGAGAAATGCCTGTC
AGAGAACATTTTCATATCGCGAAACAGAACTCGATTTTGTAAAGATTATTGAACTACTCGAGAGGTTCAAATCTGACCCT
ATTCAGAATAAACAATGGCAAAATTATTCAAAAAAATATAGCTATACAAAAGGGATTTCACTTGCAGATGTTCTTGATGA
GATGATTCGTCTCATAACAGTTCTCATTTCTATAAATTCTGATTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7595.72 Da        Isoelectric Point: 7.7889

>AT225596 WP_230233553.1 NZ_CP087584:2893650-2893850 [Providencia rettgeri]
ITVAPELCEQARRAKLNLSAILTCALQAELKRLEAQKWKNENIEGFNQLNRINEEYGLLSDKYKGF

Download         Length: 201 bp

>AT225596 NZ_CP121201:c755197-754607 [Streptococcus pluranimalium]
ATGTCAAAAAAAGAGATTCTACTCGATTTTATAGAAAAGAACAATGGAATTGTCACAAACAAAGATTGTAAAGCACTAGG
TATTCCAACAATATATCTGACAAGACTAGAGAAAGAAGGCATTATCTTCCGAGTTGAAAAAGGTATTTTCCTAACCCAAA
ACGGAGACTATGATGAATACTACTTCTTTCAATATCGTTTTCCTAAGGCTATTTTCTCTTATATTTCGGCACTGTATCTA
CAACAGTTTACAGATGAAATTCCACAATATTTTGATGTGACAGTTCCTAGAGGCTACCGCTTTAATACTCCTCCAGCTAA
TCTAAATATTCACTTTGTCTCTAAAGAATACAGCGAGCTGGGAATGACTACTGTACCTACTCCTTTGGGAAACAACGTAA
GGGTATATGATTTTGAACGTATTATTTGTGATTTTGTAATACATCGAGAAAAGATTGATTCCGAACTCTTTGTCAAGACA
CTTCAATCTTATGGGAACTATCCTAAAAAAAATCTAGCAAAACTCTATGAATATGCGACAAAAATGAATACTTTAGAAAA
AGTTAAACAAACTCTGGAGGTTCTAATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References