Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 2379956..2380875 | Replicon | chromosome |
| Accession | NZ_CP087584 | ||
| Organism | Providencia rettgeri strain L1 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A1J0E7D4 |
| Locus tag | LMY39_RS10550 | Protein ID | WP_042843809.1 |
| Coordinates | 2380414..2380875 (+) | Length | 154 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | LMY39_RS10545 | Protein ID | WP_048607179.1 |
| Coordinates | 2379956..2380417 (+) | Length | 154 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LMY39_RS10510 (LMY39_10510) | 2375062..2375526 | - | 465 | WP_129465904.1 | NUDIX domain-containing protein | - |
| LMY39_RS10515 (LMY39_10515) | 2375550..2375936 | - | 387 | WP_048607185.1 | cytidine deaminase | - |
| LMY39_RS10520 (LMY39_10520) | 2376355..2376813 | + | 459 | WP_042843802.1 | GNAT family N-acetyltransferase | - |
| LMY39_RS10525 (LMY39_10525) | 2376873..2377514 | - | 642 | WP_221078261.1 | leucine efflux protein LeuE | - |
| LMY39_RS10530 (LMY39_10530) | 2378201..2378902 | + | 702 | WP_048607181.1 | AzlC family ABC transporter permease | - |
| LMY39_RS10535 (LMY39_10535) | 2378899..2379213 | + | 315 | WP_042843806.1 | AzlD domain-containing protein | - |
| LMY39_RS10540 (LMY39_10540) | 2379399..2379866 | + | 468 | WP_042843807.1 | DUF1456 family protein | - |
| LMY39_RS10545 (LMY39_10545) | 2379956..2380417 | + | 462 | WP_048607179.1 | DUF2384 domain-containing protein | Antitoxin |
| LMY39_RS10550 (LMY39_10550) | 2380414..2380875 | + | 462 | WP_042843809.1 | RES domain-containing protein | Toxin |
| LMY39_RS10555 (LMY39_10555) | 2380884..2381774 | - | 891 | WP_042843811.1 | LysR family transcriptional regulator | - |
| LMY39_RS10560 (LMY39_10560) | 2381818..2382777 | - | 960 | WP_181469296.1 | acetyl-CoA carboxylase carboxyl transferase subunit alpha | - |
| LMY39_RS10565 (LMY39_10565) | 2382884..2383306 | - | 423 | WP_042843814.1 | helix-turn-helix domain-containing protein | - |
| LMY39_RS10570 (LMY39_10570) | 2383363..2383896 | - | 534 | WP_226619150.1 | GNAT family N-acetyltransferase | - |
| LMY39_RS10575 (LMY39_10575) | 2383913..2385373 | - | 1461 | WP_230233546.1 | AMP nucleosidase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 154 a.a. Molecular weight: 17499.99 Da Isoelectric Point: 6.4846
>T225595 WP_042843809.1 NZ_CP087584:2380414-2380875 [Providencia rettgeri]
MILYRLIKSDFAHDAWSGQGARLYGGRWNHKGTPAIYTSTSISLAALEILVHINQDTVLNHFTLLSIEINDRYVMKLSVE
HLPDDWQRDPAPTSTMDIGTTWLTNQDSLALIVPSCIIPYEYNAIINPMHPQFQKVTQTIKPLDFAFDPRFNR
MILYRLIKSDFAHDAWSGQGARLYGGRWNHKGTPAIYTSTSISLAALEILVHINQDTVLNHFTLLSIEINDRYVMKLSVE
HLPDDWQRDPAPTSTMDIGTTWLTNQDSLALIVPSCIIPYEYNAIINPMHPQFQKVTQTIKPLDFAFDPRFNR
Download Length: 462 bp
>T225595 NZ_CP121200:c120970-120554 [Escherichia coli]
GTGAACAAGACTTATATGCTTGATACCTGTATCTGCTCGTTCATCATGCGTGAACAGCCAGAAGCCGTCCTGAAGCGTCT
GGAGCAGGCGGTGCTACGCGGCCACCGTATAGTGGTCTCGGCCATCACCTACTCTGAAATGCGCTTCGGGGCTACCGGCC
CAAAGGCCTCACCACGTCACGTCCAACTGGTCGATGAATTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCC
GCAGTAGACGCCACCACGAAGATTAAAGTGGCACTGCGGCTGGCCGGGACGCCGATCGGCCCGAACGACACGGCGATTGC
CGGGCACGCCATCGCCGCCGGGGCGATACTGGTAACGAATAATACAAGAGAATTTGAGCGAGTGCCTGACCTGGTGCTGG
AAGACTGGGTGAAGTAA
GTGAACAAGACTTATATGCTTGATACCTGTATCTGCTCGTTCATCATGCGTGAACAGCCAGAAGCCGTCCTGAAGCGTCT
GGAGCAGGCGGTGCTACGCGGCCACCGTATAGTGGTCTCGGCCATCACCTACTCTGAAATGCGCTTCGGGGCTACCGGCC
CAAAGGCCTCACCACGTCACGTCCAACTGGTCGATGAATTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCC
GCAGTAGACGCCACCACGAAGATTAAAGTGGCACTGCGGCTGGCCGGGACGCCGATCGGCCCGAACGACACGGCGATTGC
CGGGCACGCCATCGCCGCCGGGGCGATACTGGTAACGAATAATACAAGAGAATTTGAGCGAGTGCCTGACCTGGTGCTGG
AAGACTGGGTGAAGTAA
Antitoxin
Download Length: 154 a.a. Molecular weight: 17056.55 Da Isoelectric Point: 9.9812
>AT225595 WP_048607179.1 NZ_CP087584:2379956-2380417 [Providencia rettgeri]
MRNYIPALPTQPATPPFKPLWRFAGLPAERGIELTHFLRQGLSVTVLDNIQEWSGISKSELLRISGINERNVARRRNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKSMASDWLNHPVKGLGHTRPIELIATESGALEVIDLIGRIEHGVFS
MRNYIPALPTQPATPPFKPLWRFAGLPAERGIELTHFLRQGLSVTVLDNIQEWSGISKSELLRISGINERNVARRRNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKSMASDWLNHPVKGLGHTRPIELIATESGALEVIDLIGRIEHGVFS
Download Length: 462 bp
>AT225595 NZ_CP121200:c121197-120967 [Escherichia coli]
ATGAGAACCGTATCGATATTCAAAAATGGCAACAACCGCGCCATCCGTCTGCCTCGTGATCTGGATTTTGAGGGGGTGAG
CGAGCTCGAGATCGTCCGGGAAGGGGACAGCATCATCCTGCGCCCCGTCCGGCCAACCTGGGGATCATTCCTAGAGTACG
AAAAAGCCGATCCAGATTTTATGGCGGAGCGCGAGGATGTTGTCAGCGACGAAGGGCGATTTAACCTGTGA
ATGAGAACCGTATCGATATTCAAAAATGGCAACAACCGCGCCATCCGTCTGCCTCGTGATCTGGATTTTGAGGGGGTGAG
CGAGCTCGAGATCGTCCGGGAAGGGGACAGCATCATCCTGCGCCCCGTCCGGCCAACCTGGGGATCATTCCTAGAGTACG
AAAAAGCCGATCCAGATTTTATGGCGGAGCGCGAGGATGTTGTCAGCGACGAAGGGCGATTTAACCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|