Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1069414..1069648 | Replicon | chromosome |
| Accession | NZ_CP087564 | ||
| Organism | Escherichia coli strain CM2010-0578/1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1069415..1069518 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1069414..1069648 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOF66_RS05555 | 1066362..1067414 | + | 1053 | WP_001004417.1 | RecT family recombinase | - |
| LOF66_RS05560 | 1067478..1067672 | + | 195 | WP_274480430.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| LOF66_RS05565 | 1067665..1067853 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 1067671..1067849 | - | 179 | NuclAT_1 | - | - |
| - | 1067671..1067849 | - | 179 | NuclAT_1 | - | - |
| - | 1067671..1067849 | - | 179 | NuclAT_1 | - | - |
| - | 1067671..1067849 | - | 179 | NuclAT_1 | - | - |
| LOF66_RS05570 | 1067960..1068241 | + | 282 | WP_001311878.1 | excisionase | - |
| LOF66_RS05575 | 1068207..1069283 | + | 1077 | WP_033544538.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1069414..1069648 | + | 235 | - | - | Antitoxin |
| - | 1069415..1069518 | - | 104 | - | - | Toxin |
| LOF66_RS05580 | 1069676..1070017 | - | 342 | WP_000976476.1 | YebY family protein | - |
| LOF66_RS05585 | 1070030..1070902 | - | 873 | WP_274480431.1 | copper homeostasis membrane protein CopD | - |
| LOF66_RS05590 | 1070906..1071280 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| LOF66_RS05595 | 1071419..1071649 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| LOF66_RS05600 | 1071751..1072407 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| LOF66_RS05605 | 1072431..1073093 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1011902..1073093 | 61191 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T225476 NZ_CP087564:c1069518-1069415 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT225476 NZ_CP087564:1069414-1069648 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
