Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2383152..2383423 Replicon chromosome
Accession NZ_CP087377
Organism Escherichia coli strain RIVM_C019217

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2383282..2383385 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2383152..2383423 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN359_RS11660 2379707..2380369 - 663 WP_000944256.1 exodeoxyribonuclease X -
LN359_RS11665 2380393..2381049 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
LN359_RS11670 2381151..2381381 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LN359_RS11675 2381520..2381894 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LN359_RS11680 2381898..2382770 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
LN359_RS11685 2382783..2383124 + 342 WP_000976472.1 YebY family protein -
- 2383152..2383423 - 272 - - Antitoxin
- 2383282..2383385 + 104 - - Toxin
LN359_RS11690 2383520..2384176 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
LN359_RS11695 2384177..2384368 - 192 WP_001296140.1 YebW family protein -
LN359_RS11700 2384473..2384709 - 237 WP_001295499.1 YebV family protein -
LN359_RS11705 2384827..2386266 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2310582..2399263 88681


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T225399 NZ_CP087377:2383282-2383385 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT225399 NZ_CP087377:c2383423-2383152 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References