Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4130208..4130881 Replicon chromosome
Accession NC_010002
Organism Delftia acidovorans SPH-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DACI_RS18880 Protein ID WP_050771858.1
Coordinates 4130208..4130618 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DACI_RS31495 Protein ID WP_012205584.1
Coordinates 4130615..4130881 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DACI_RS18865 4125252..4126325 + 1074 WP_192812290.1 methylmalonyl Co-A mutase-associated GTPase MeaB -
DACI_RS18870 4126382..4127914 + 1533 WP_012205581.1 acyl-CoA carboxylase subunit beta -
DACI_RS18875 4128126..4130174 + 2049 WP_012205582.1 acetyl-CoA carboxylase biotin carboxylase subunit -
DACI_RS18880 4130208..4130618 - 411 WP_050771858.1 type II toxin-antitoxin system VapC family toxin Toxin
DACI_RS31495 4130615..4130881 - 267 WP_012205584.1 DNA-binding protein Antitoxin
DACI_RS18890 4131121..4132092 + 972 WP_012205585.1 chemotaxis protein -
DACI_RS18895 4132129..4133223 - 1095 WP_012205586.1 LacI family DNA-binding transcriptional regulator -
DACI_RS18900 4133449..4133967 + 519 WP_043781962.1 gluconokinase -
DACI_RS18905 4133986..4134492 + 507 WP_012205588.1 TRAP transporter small permease -
DACI_RS18910 4134505..4135785 + 1281 WP_012205589.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15189.48 Da        Isoelectric Point: 7.3849

>T22534 WP_050771858.1 NC_010002:c4130618-4130208 [Delftia acidovorans SPH-1]
MMLYMLDTNAASEAIRGNPLFDARLQALAPGQWCVSAVTCSELRYGIARRPEAVRLARIVEAFLHITAILPWDARAANQH
GQLRAYLRAQGSPIGDFDEMIAAHALALDAILVTDNVRHFERISGLRIENWLRQGH

Download         Length: 411 bp

>T22534 NC_010002:c4130618-4130208 [Delftia acidovorans SPH-1]
ATGATGCTGTACATGCTGGACACCAATGCCGCCAGCGAAGCCATCCGGGGCAATCCCTTGTTTGATGCGCGCTTGCAAGC
CCTCGCACCAGGGCAGTGGTGCGTTAGTGCAGTGACCTGTTCCGAGCTGCGCTATGGAATTGCCCGGCGGCCCGAGGCGG
TACGGCTGGCACGGATCGTGGAGGCGTTCCTGCACATCACCGCCATCCTGCCCTGGGACGCCAGGGCGGCCAACCAGCAT
GGTCAGTTGCGTGCTTATCTGCGTGCCCAGGGCTCGCCGATTGGAGACTTCGACGAAATGATCGCCGCACATGCGCTGGC
CCTGGACGCGATCCTGGTCACAGACAATGTGCGGCATTTCGAACGCATTTCCGGGCTCAGGATCGAAAACTGGCTGCGCC
AGGGGCATTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10097.25 Da        Isoelectric Point: 4.6388

>AT22534 WP_012205584.1 NC_010002:c4130881-4130615 [Delftia acidovorans SPH-1]
MPPVTAQLFATDGVQAVKLPAEFRFEDRAEVYIRRDENTGDVILSTIPRADWSEFMRLRHQLGHAAESALPVRQQGSEQR
DPFQGWEE

Download         Length: 267 bp

>AT22534 NC_010002:c4130881-4130615 [Delftia acidovorans SPH-1]
ATGCCACCCGTTACCGCCCAACTTTTCGCCACCGATGGCGTTCAAGCCGTAAAGCTGCCTGCCGAGTTTCGCTTCGAAGA
TCGAGCCGAGGTGTATATCCGCCGCGATGAAAACACCGGAGACGTCATTCTTTCGACCATTCCTCGCGCGGACTGGAGTG
AATTCATGCGGCTGCGCCACCAGCTGGGGCATGCGGCCGAGTCGGCCCTCCCCGTGCGCCAACAGGGCAGCGAGCAACGC
GATCCCTTCCAAGGTTGGGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References