Detailed information of TA system TA022530

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 89990..91446
• Replicon: chromosome
• Accession: NC_010002
• Organism: Delftia acidovorans SPH-1

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: A9BQM7
• Locus tag: DACI_RS00410
• Protein ID: WP_012202022.1
• Coordinates: 89990..90835 (-)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: A9BQM8
• Locus tag: DACI_RS00415
• Protein ID: WP_012202023.1
• Coordinates: 90832..91446 (-)
• Length: 205 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DACI_RS00385	85325..86488	+	1164	WP_012202017.1	ABC transporter substrate-binding protein	-
DACI_RS00390	86539..87411	+	873	WP_012202018.1	branched-chain amino acid ABC transporter permease	-
DACI_RS00395	87415..88500	+	1086	WP_012202019.1	branched-chain amino acid ABC transporter permease	-
DACI_RS00400	88493..89251	+	759	WP_012202020.1	ABC transporter ATP-binding protein	-
DACI_RS00405	89256..89957	+	702	WP_043780178.1	ABC transporter ATP-binding protein	-
DACI_RS00410	89990..90835	-	846	WP_012202022.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
DACI_RS00415	90832..91446	-	615	WP_012202023.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
DACI_RS00420	91554..92027	-	474	WP_012202024.1	hotdog fold thioesterase	-
DACI_RS00425	92166..93680	-	1515	WP_012202025.1	acetyl-CoA hydrolase/transferase family protein	-
DACI_RS00430	93888..95195	-	1308	WP_012202026.1	NCS2 family nucleobase:cation symporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-258)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (12-57)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 31130.80 Da
• Isoelectric Point: 7.2653

>T22530 WP_012202022.1 NC_010002:c90835-89990 [Delftia acidovorans SPH-1]
MSRDIAASIRARLKQCADARRQDFNLTLTHYGLERLLYRLSISPHADSYLLKGALLFAIWYEQPHRPTRDADLLGFGLDD
VDSAVSAFREICGIAVDDGIAFDAASVRGTTIRKEAGYGEVRIDLRATLDGARITLQVDIGFGDAVTPSPQAIRYPVLLD
GLPAPQLRSYPKYTVVAEKLHAICLLGMANTRMKDYFDLWVLMTEGTLDPAELRRAMKATFERRQLALPAGLPAGLSDGF
SSDAAKQAQWAAFLKKNRLEALELAPVVARLREEFQQCGIF

Nucleotide

• Length: 846 bp

>T22530 NC_010002:c90835-89990 [Delftia acidovorans SPH-1]
ATGAGCCGCGATATCGCAGCCTCGATCCGTGCACGTTTGAAGCAATGCGCGGACGCCCGCAGGCAGGACTTCAACCTCAC
GCTCACCCACTATGGCCTGGAGCGCCTGCTGTACCGCCTGTCCATCTCGCCCCATGCGGACAGCTATCTGCTCAAGGGCG
CACTGCTGTTCGCCATCTGGTACGAGCAGCCGCACAGGCCGACCCGCGACGCCGATCTGCTGGGCTTTGGCCTGGACGAC
GTTGACTCGGCGGTGAGCGCTTTCCGCGAGATCTGCGGGATTGCCGTGGACGACGGCATTGCCTTCGATGCCGCGTCGGT
GCGTGGAACCACCATCCGCAAGGAAGCCGGCTATGGCGAAGTACGGATTGACCTGCGCGCCACGCTGGACGGTGCACGCA
TCACGCTGCAGGTGGACATAGGCTTCGGCGATGCCGTGACACCATCGCCACAAGCCATCCGCTACCCCGTGCTGCTCGAC
GGCCTGCCCGCACCGCAACTGCGCAGCTACCCCAAGTACACCGTGGTGGCCGAAAAACTCCACGCGATATGCCTGCTGGG
CATGGCCAATACCCGGATGAAGGACTACTTCGATCTCTGGGTGTTGATGACCGAAGGCACGCTGGACCCTGCCGAACTGC
GGCGCGCCATGAAAGCGACCTTCGAGCGCCGCCAACTCGCGCTGCCCGCGGGCCTGCCTGCCGGATTGAGCGATGGTTTC
AGCAGCGATGCGGCCAAGCAGGCGCAGTGGGCCGCCTTCCTGAAGAAGAACCGGCTTGAAGCGCTGGAGCTGGCCCCTGT
CGTGGCAAGGCTGCGAGAGGAATTCCAGCAATGCGGCATCTTCTGA

Antitoxin

Protein

• Length: 205 a.a.
• Molecular weight: 21868.45 Da
• Isoelectric Point: 9.5757

>AT22530 WP_012202023.1 NC_010002:c91446-90832 [Delftia acidovorans SPH-1]
MPAPGSALEQAVLALAEQRPLLRARDLAALGLPTMALSRLVAAGRLERVARGLYSLPGRPLSEHRSLAEVALRVPQGVVC
LLSALRVHGIGTQAPFEVWMAIPHHSPTPRIDQPALRAIRMSGAALSEGVETLQIDGVGVAVFNASKTVADCFKYRNKIG
LDVALEALRDGWAQGKLTADALWHYAAIDRVSNVMRPYLESIAA

Nucleotide

• Length: 615 bp

>AT22530 NC_010002:c91446-90832 [Delftia acidovorans SPH-1]
ATGCCCGCTCCTGGCTCCGCGCTCGAACAAGCCGTTCTGGCACTGGCCGAACAACGGCCGCTGCTGCGCGCACGCGACCT
TGCCGCGCTTGGCCTGCCGACCATGGCGCTGAGCCGGCTGGTCGCGGCAGGCCGCCTTGAACGCGTTGCACGCGGCCTGT
ACAGCCTGCCGGGCCGGCCGCTCAGCGAGCACCGCTCGCTGGCGGAAGTGGCCCTGCGCGTACCGCAAGGGGTGGTCTGC
CTGCTGTCCGCGCTGCGGGTCCACGGCATAGGAACGCAGGCACCCTTCGAGGTGTGGATGGCCATTCCCCATCACTCGCC
CACGCCCCGCATAGACCAGCCTGCATTGCGCGCCATCCGCATGTCCGGTGCGGCACTGTCCGAAGGCGTGGAAACTCTGC
AGATCGATGGCGTCGGTGTCGCCGTCTTCAACGCATCGAAGACCGTGGCCGATTGCTTCAAGTACCGCAACAAGATCGGC
CTGGATGTGGCGTTGGAAGCACTGCGCGACGGATGGGCGCAGGGCAAGCTGACGGCCGACGCGCTCTGGCACTACGCCGC
CATCGACCGCGTCAGCAATGTGATGCGCCCCTATCTCGAAAGCATCGCCGCATGA

Structures

Toxin

• AlphaFold DB: A9BQM7

Antitoxin

• AlphaFold DB: A9BQM8