Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /DUF1778(antitoxin) |
| Location | 904490..905286 | Replicon | chromosome |
| Accession | NC_009997 | ||
| Organism | Shewanella baltica OS195 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | B8ECY2 |
| Locus tag | SBAL195_RS03900 | Protein ID | WP_011847801.1 |
| Coordinates | 904756..905286 (+) | Length | 177 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A9L131 |
| Locus tag | SBAL195_RS03895 | Protein ID | WP_012196652.1 |
| Coordinates | 904490..904759 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SBAL195_RS03875 | 899802..901994 | + | 2193 | WP_012196650.1 | TonB-dependent siderophore receptor | - |
| SBAL195_RS03880 | 902095..902769 | + | 675 | WP_006086056.1 | Fe2+-dependent dioxygenase | - |
| SBAL195_RS03885 | 903207..903692 | + | 486 | WP_012196651.1 | hypothetical protein | - |
| SBAL195_RS03890 | 903823..904287 | + | 465 | WP_041411001.1 | hypothetical protein | - |
| SBAL195_RS03895 | 904490..904759 | + | 270 | WP_012196652.1 | DUF1778 domain-containing protein | Antitoxin |
| SBAL195_RS03900 | 904756..905286 | + | 531 | WP_011847801.1 | GNAT family N-acetyltransferase | Toxin |
| SBAL195_RS03905 | 905612..906427 | + | 816 | WP_012196653.1 | hypothetical protein | - |
| SBAL195_RS03910 | 906411..906800 | + | 390 | WP_080514245.1 | HEPN domain-containing protein | - |
| SBAL195_RS25045 | 906875..907054 | + | 180 | WP_150102373.1 | hypothetical protein | - |
| SBAL195_RS03915 | 907120..907413 | - | 294 | WP_012196656.1 | hypothetical protein | - |
| SBAL195_RS03920 | 907410..907730 | - | 321 | WP_012196657.1 | hypothetical protein | - |
| SBAL195_RS03925 | 907727..907957 | - | 231 | WP_011847800.1 | hypothetical protein | - |
| SBAL195_RS03930 | 907954..908232 | - | 279 | WP_012196658.1 | hypothetical protein | - |
| SBAL195_RS03935 | 908233..908526 | - | 294 | WP_012196659.1 | hypothetical protein | - |
| SBAL195_RS03940 | 908557..908904 | - | 348 | WP_012196660.1 | hypothetical protein | - |
| SBAL195_RS03945 | 908930..909190 | - | 261 | WP_006082040.1 | pyocin activator PrtN family protein | - |
| SBAL195_RS03950 | 909187..909540 | - | 354 | WP_012196661.1 | hypothetical protein | - |
| SBAL195_RS03955 | 909693..909980 | + | 288 | WP_048908671.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 895378..946696 | 51318 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 177 a.a. Molecular weight: 19727.98 Da Isoelectric Point: 8.6014
>T22522 WP_011847801.1 NC_009997:904756-905286 [Shewanella baltica OS195]
VSYSKTFKELDKSQHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMVLPAVTPLPNQKYPICSFYTIAPSSICRDTLPQ
AMGKKLPRYPIPVFLLAQLAVHKEFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
RVRMFIPMKTVGQLFT
VSYSKTFKELDKSQHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMVLPAVTPLPNQKYPICSFYTIAPSSICRDTLPQ
AMGKKLPRYPIPVFLLAQLAVHKEFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
RVRMFIPMKTVGQLFT
Download Length: 531 bp
>T22522 NC_009997:904756-905286 [Shewanella baltica OS195]
GTGAGTTATTCCAAGACTTTCAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCTGCGAAACACATGCAAGCAGGTATTAGCCGTACAATGGTTTTACCTGCTGTTACGC
CATTACCCAATCAAAAATATCCAATTTGCTCATTTTATACTATCGCCCCAAGTTCAATTTGCCGTGATACCTTACCGCAA
GCCATGGGTAAAAAGTTACCACGCTATCCCATTCCGGTTTTTCTGCTTGCTCAACTTGCTGTCCATAAAGAGTTTCATGG
TAGTGGGCTAGGTAAAGCTAGCTTAATCAAAGCACTAGAATACCTTTGGGAGATTAACGCTCACATGCGAGCTTATGCCA
TTGTTGTCGATTGCTTAACTGGCCAAGCTGAATCATTTTACGCTAAGTACGGTTTCGAGGTTCTTTGTGAAATCAACGGT
CGTGTAAGAATGTTTATTCCAATGAAAACAGTCGGTCAGTTGTTTACTTAG
GTGAGTTATTCCAAGACTTTCAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCTGCGAAACACATGCAAGCAGGTATTAGCCGTACAATGGTTTTACCTGCTGTTACGC
CATTACCCAATCAAAAATATCCAATTTGCTCATTTTATACTATCGCCCCAAGTTCAATTTGCCGTGATACCTTACCGCAA
GCCATGGGTAAAAAGTTACCACGCTATCCCATTCCGGTTTTTCTGCTTGCTCAACTTGCTGTCCATAAAGAGTTTCATGG
TAGTGGGCTAGGTAAAGCTAGCTTAATCAAAGCACTAGAATACCTTTGGGAGATTAACGCTCACATGCGAGCTTATGCCA
TTGTTGTCGATTGCTTAACTGGCCAAGCTGAATCATTTTACGCTAAGTACGGTTTCGAGGTTCTTTGTGAAATCAACGGT
CGTGTAAGAATGTTTATTCCAATGAAAACAGTCGGTCAGTTGTTTACTTAG
Antitoxin
Download Length: 90 a.a. Molecular weight: 9931.43 Da Isoelectric Point: 4.9059
>AT22522 WP_012196652.1 NC_009997:904490-904759 [Shewanella baltica OS195]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESITVKADVFDQFIMACDEAKAPNKALREAV
AFTKRGEFK
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESITVKADVFDQFIMACDEAKAPNKALREAV
AFTKRGEFK
Download Length: 270 bp
>AT22522 NC_009997:904490-904759 [Shewanella baltica OS195]
ATGGCGACTGCAAGACTTGATATCCGTTTGGATGAAGAGATCAAAGCTAAGGCTGAGAAAGCCTCGGCTTTGCTTGGTTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATTCAACTCAGGTGATTGCTGAGCATGAAAGCATTACTG
TTAAAGCTGATGTATTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGCCCCGAACAAGGCATTGCGTGAAGCGGTT
GCATTTACTAAACGTGGTGAGTTTAAGTGA
ATGGCGACTGCAAGACTTGATATCCGTTTGGATGAAGAGATCAAAGCTAAGGCTGAGAAAGCCTCGGCTTTGCTTGGTTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATTCAACTCAGGTGATTGCTGAGCATGAAAGCATTACTG
TTAAAGCTGATGTATTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGCCCCGAACAAGGCATTGCGTGAAGCGGTT
GCATTTACTAAACGTGGTGAGTTTAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|