Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-parE/RHH(antitoxin) |
| Location | 3974411..3974964 | Replicon | chromosome |
| Accession | NZ_CP087204 | ||
| Organism | Pseudomonas sp. B21-054 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | LOY70_RS17295 | Protein ID | WP_265028609.1 |
| Coordinates | 3974411..3974704 (-) | Length | 98 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | LOY70_RS17300 | Protein ID | WP_265028610.1 |
| Coordinates | 3974692..3974964 (-) | Length | 91 a.a. |
Genomic Context
Location: 3969985..3970746 (762 bp)
Type: Others
Protein ID: WP_265028606.1
Type: Others
Protein ID: WP_265028606.1
Location: 3970743..3972119 (1377 bp)
Type: Others
Protein ID: WP_265028607.1
Type: Others
Protein ID: WP_265028607.1
Location: 3972116..3974290 (2175 bp)
Type: Others
Protein ID: WP_265028608.1
Type: Others
Protein ID: WP_265028608.1
Location: 3975301..3976980 (1680 bp)
Type: Others
Protein ID: WP_265028611.1
Type: Others
Protein ID: WP_265028611.1
Location: 3974411..3974704 (294 bp)
Type: Toxin
Protein ID: WP_265028609.1
Type: Toxin
Protein ID: WP_265028609.1
Location: 3974692..3974964 (273 bp)
Type: Antitoxin
Protein ID: WP_265028610.1
Type: Antitoxin
Protein ID: WP_265028610.1
Location: 3976997..3977815 (819 bp)
Type: Others
Protein ID: WP_265028612.1
Type: Others
Protein ID: WP_265028612.1
Location: 3978795..3979010 (216 bp)
Type: Others
Protein ID: WP_265028613.1
Type: Others
Protein ID: WP_265028613.1
Location: 3979332..3979940 (609 bp)
Type: Others
Protein ID: WP_265028614.1
Type: Others
Protein ID: WP_265028614.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOY70_RS17280 (LOY70_17235) | 3969985..3970746 | + | 762 | WP_265028606.1 | efflux RND transporter periplasmic adaptor subunit | - |
| LOY70_RS17285 (LOY70_17240) | 3970743..3972119 | + | 1377 | WP_265028607.1 | biotin/lipoyl-binding protein | - |
| LOY70_RS17290 (LOY70_17245) | 3972116..3974290 | + | 2175 | WP_265028608.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| LOY70_RS17295 (LOY70_17250) | 3974411..3974704 | - | 294 | WP_265028609.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LOY70_RS17300 (LOY70_17255) | 3974692..3974964 | - | 273 | WP_265028610.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| LOY70_RS17305 (LOY70_17260) | 3975301..3976980 | + | 1680 | WP_265028611.1 | thiamine pyrophosphate-binding protein | - |
| LOY70_RS17310 (LOY70_17265) | 3976997..3977815 | - | 819 | WP_265028612.1 | helix-turn-helix transcriptional regulator | - |
| LOY70_RS17320 (LOY70_17275) | 3978795..3979010 | - | 216 | WP_265028613.1 | DUF6434 domain-containing protein | - |
| LOY70_RS17325 (LOY70_17280) | 3979332..3979940 | - | 609 | WP_265028614.1 | LysE family translocator | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11053.68 Da Isoelectric Point: 5.7302
>T225138 WP_265028609.1 NZ_CP087204:c3974704-3974411 [Pseudomonas sp. B21-054]
VPRLILTAGAGEGLERCRRFLLEKDPQVTRRAAQAIEQQLMRLETDPHVGRPVDDMPELRELVIAFGDAGYVALYRFVPA
EETVYVLAFRHQREAGY
VPRLILTAGAGEGLERCRRFLLEKDPQVTRRAAQAIEQQLMRLETDPHVGRPVDDMPELRELVIAFGDAGYVALYRFVPA
EETVYVLAFRHQREAGY
Download Length: 294 bp
>T225138 NZ_CP121003:c2693321-2693218 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 91 a.a. Molecular weight: 10515.62 Da Isoelectric Point: 4.8838
>AT225138 WP_265028610.1 NZ_CP087204:c3974964-3974692 [Pseudomonas sp. B21-054]
MATSIKIDEDLKYRIQQLASARQRSAHWIMREALSQYVVREEARESFKQEALASWTAYQETGQHLTGAETRDWLKTWGTD
EESELPTCHD
MATSIKIDEDLKYRIQQLASARQRSAHWIMREALSQYVVREEARESFKQEALASWTAYQETGQHLTGAETRDWLKTWGTD
EESELPTCHD
Download Length: 273 bp
>AT225138 NZ_CP121003:2693216-2693361 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG