Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1629491..1630530 Replicon chromosome
Accession NZ_CP087204
Organism Pseudomonas sp. B21-054

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag LOY70_RS07235 Protein ID WP_123414765.1
Coordinates 1629491..1630066 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag LOY70_RS07240 Protein ID WP_265035033.1
Coordinates 1630063..1630530 (-) Length 156 a.a.

Genomic Context

LOY70_RS07210LOY70_RS07215LOY70_RS07220LOY70_RS07225LOY70_RS07230LOY70_RS07235LOY70_RS07240LOY70_RS07250LOY70_RS07255LOY70_RS07260LOY70_RS07265
Location: 1626235..1626627 (393 bp)
Type: Others
Protein ID: WP_265035026.1
Location: 1626624..1626974 (351 bp)
Type: Others
Protein ID: WP_265035028.1
Location: 1627026..1628188 (1163 bp)
Type: Others
Protein ID: WP_265035029.1
Location: 1628213..1628815 (603 bp)
Type: Others
Protein ID: WP_265035031.1
Location: 1629209..1629385 (177 bp)
Type: Others
Protein ID: Protein_1428
Location: 1629491..1630066 (576 bp)
Type: Toxin
Protein ID: WP_123414765.1
Location: 1630063..1630530 (468 bp)
Type: Antitoxin
Protein ID: WP_265035033.1
Location: 1631366..1632250 (885 bp)
Type: Others
Protein ID: WP_265035035.1
Location: 1632562..1633254 (693 bp)
Type: Others
Protein ID: WP_265035037.1
Location: 1633290..1633508 (219 bp)
Type: Others
Protein ID: WP_123414761.1
Location: 1633501..1634112 (612 bp)
Type: Others
Protein ID: Protein_1434
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LOY70_RS07210 (LOY70_07190)1626235..1626627+393WP_265035026.1TauD/TfdA family dioxygenase-
LOY70_RS07215 (LOY70_07195)1626624..1626974+351WP_265035028.1hypothetical protein-
LOY70_RS07220 (LOY70_07200)1627026..1628188+1163WP_265035029.1IS3 family transposase-
LOY70_RS07225 (LOY70_07205)1628213..1628815+603WP_265035031.1hypothetical protein-
LOY70_RS07230 (LOY70_07210)1629209..1629385-177Protein_1428transposase domain-containing protein-
LOY70_RS07235 (LOY70_07215)1629491..1630066-576WP_123414765.1PIN domain-containing proteinToxin
LOY70_RS07240 (LOY70_07220)1630063..1630530-468WP_265035033.1helix-turn-helix domain-containing proteinAntitoxin
LOY70_RS07250 (LOY70_07230)1631366..1632250-885WP_265035035.1alpha/beta hydrolase-
LOY70_RS07255 (LOY70_07235)1632562..1633254-693WP_265035037.1pseudouridine synthase-
LOY70_RS07260 (LOY70_07240)1633290..1633508-219WP_123414761.1cysteine-rich CWC family protein-
LOY70_RS07265 (LOY70_07245)1633501..1634112-612Protein_1434GGDEF domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21759.86 Da        Isoelectric Point: 5.5793

>T225135 WP_123414765.1 NZ_CP087204:c1630066-1629491 [Pseudomonas sp. B21-054]
MRHSPYTAVYDANVLYPAPLRDFLMRLALTGAYRARWSAQIHDEWKRNLLVKRPDLTVDQVNRTSALMDRAIPDALVTDY
ESIVAQLDLPDADDRHVLAAAIKCNASAIVTFNLKDFPQAALDSWGIEALHPDEFIVDLWDLDQAAVVEAAQRQRASLKN
PPHTVREYLDKLLQQKLPETVKLLSHFEYVL

Download         Length: 576 bp

>T225135 NZ_CP121003:836166-836564 [Salmonella enterica]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTCTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAACTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCGGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAATTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17377.85 Da        Isoelectric Point: 5.0703

>AT225135 WP_265035033.1 NZ_CP087204:c1630530-1630063 [Pseudomonas sp. B21-054]
MTTADLTRAVLPDEREIAVAVESSRQIAAFLSAKQETQRIELVDGEQQRQVVELPIYAIRLLGEILSELALGNTVKVVPI
HAELTTQEGADLLNVSRPHLVKLLDEGVMPHTKTGRHRRIKFADLMEYKNRREQDSHAILDELAAQAQELGMGYE

Download         Length: 468 bp

>AT225135 NZ_CP121003:835939-836166 [Salmonella enterica]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGTAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References