225130

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 490616..491205 Replicon chromosome
Accession NZ_CP087203
Organism Pseudomonas sp. B21-056

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LOY67_RS02170 Protein ID WP_265065745.1
Coordinates 490616..490921 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY67_RS02175 Protein ID WP_041021981.1
Coordinates 490918..491205 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY67_RS02145 (LOY67_02145) 485694..486566 + 873 WP_265065740.1 type II secretion system protein GspK -
LOY67_RS02150 (LOY67_02150) 486538..487641 + 1104 WP_265065741.1 type II secretion system protein GspL -
LOY67_RS02155 (LOY67_02155) 487641..488096 + 456 WP_265065742.1 type II secretion system protein M -
LOY67_RS02160 (LOY67_02160) 488260..489537 - 1278 WP_265065743.1 MFS transporter -
LOY67_RS02165 (LOY67_02165) 489657..490571 + 915 WP_265065744.1 LysR family transcriptional regulator -
LOY67_RS02170 (LOY67_02170) 490616..490921 + 306 WP_265065745.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY67_RS02175 (LOY67_02175) 490918..491205 + 288 WP_041021981.1 putative addiction module antidote protein Antitoxin
LOY67_RS02180 (LOY67_02180) 491258..495187 - 3930 WP_265065746.1 hypothetical protein -
LOY67_RS02185 (LOY67_02185) 495574..496020 - 447 WP_265065747.1 excinuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11432.14 Da        Isoelectric Point: 10.0053

>T225130 WP_265065745.1 NZ_CP087203:490616-490921 [Pseudomonas sp. B21-056]
MTELIRSCTFSGWLSKLADSRARIRIQVRIDRMADGNLGDVKAIGEGLSEARIDYGPGYRIYFMQQGRQLIILLCGGDKS
SQTRDIKQARLIAKSWQEQNP

Download         Length: 306 bp

>T225130 NZ_CP120979:c323624-323313 [Moellerella wisconsensis]
ATGCACGTAATTTCAAGAGATCCTTTTAACCAGGCATCCAAGCGATTTCCTAACAGTGCTCAGGCGTTATCTGACGTATA
TCGAACACTTAAGCGCGATAGTTATCAGACACCCGATGAGCTTAAGAAGGTTTTCCCCAGCCTTGACCGAATGAAGTACA
GAGAGAAATGGTGGGTTATCGATATCAGTGGAAATGCGTTAAGAATGATGTTTTTCGCCGACTTTGACCGGGGAAAAATA
TTCGTGAAACACATAACGACCCACGCAGAGTACGATAAGTTGACAGATCACTACCGGAGAACAAAAGCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10427.76 Da        Isoelectric Point: 4.6412

>AT225130 WP_041021981.1 NZ_CP087203:490918-491205 [Pseudomonas sp. B21-056]
MTEQFTRWDSAEYLKTEEDMANYLDACMEEAGDDPAFIAKALGTIARARGMTQVARDAGLSRENLYRALSGEGNPEFGTI
LKVVRALGLKLHAST

Download         Length: 288 bp

>AT225130 NZ_CP120979:c323316-322900 [Moellerella wisconsensis]
ATGATGTTTCAAGACGCCGTAAAAGCGGCACAAAACCTGGTAAATCTAGTCCCGTTACTGGGAGACAGCCATTCACGCCC
GGATTATGAAAAGGCCGTTCAGTTGGTGGAGCATCTTGTCGAGAACGACCCTGACAATCCGCTCATCGATATGATTTGCG
CAAAAATAGATGCGTATGAAAATGCCGCACCTGAATTTGCAGAGTTTAACCAACGTTTAGCAGAAAGTAATGATGGTGTG
GCAGCGTTAAGAACGCTGATGGATCAATACAACCTCAATACGACAGACTTTGGAAATGAGCTCGGTTCTCGTTCATACGT
CAGCCGTATCCTCAATGGGGAACGTGGATTAACCTTGGAGCACATCAAAAATCTGTCCAAACGCTTTGGTATTCCAGCCT
CAATATTTATTCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References