Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 850313..850880 Replicon chromosome
Accession NZ_CP087202
Organism Pseudomonas asplenii strain B21-058

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY63_RS03780 Protein ID WP_090202283.1
Coordinates 850313..850603 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY63_RS03785 Protein ID WP_090202280.1
Coordinates 850593..850880 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY63_RS03755 (LOY63_03755) 846229..847311 - 1083 WP_010448448.1 endonuclease/exonuclease/phosphatase family protein -
LOY63_RS03760 (LOY63_03760) 847398..848060 - 663 WP_010448450.1 YciC family protein -
LOY63_RS03765 (LOY63_03765) 848227..848985 + 759 WP_010448452.1 DUF2076 domain-containing protein -
LOY63_RS03770 (LOY63_03770) 849184..849663 + 480 WP_010448453.1 NYN domain-containing protein -
LOY63_RS03775 (LOY63_03775) 849692..850303 + 612 WP_010448454.1 3'-5' exonuclease -
LOY63_RS03780 (LOY63_03780) 850313..850603 - 291 WP_090202283.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY63_RS03785 (LOY63_03785) 850593..850880 - 288 WP_090202280.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LOY63_RS03790 (LOY63_03790) 851348..851845 + 498 WP_265085240.1 Bro-N domain-containing protein -
LOY63_RS03795 (LOY63_03795) 852015..852476 - 462 WP_265085241.1 Lrp/AsnC family transcriptional regulator -
LOY63_RS03800 (LOY63_03800) 852635..853525 + 891 WP_265085242.1 drug/metabolite exporter YedA -
LOY63_RS03805 (LOY63_03805) 853597..854934 + 1338 WP_029534216.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11249.11 Da        Isoelectric Point: 10.4443

>T225125 WP_090202283.1 NZ_CP087202:c850603-850313 [Pseudomonas asplenii]
MGAEYSVEWDPKALKELRSLDTALRLQLLRKLEERRHAPRVQSDALHGLKDCYKIKLRAAGYRLVYRVEDERIVVVVLAI
GKRERSAVYEQARKRT

Download         Length: 291 bp

>T225125 NZ_CP120978:2875980-2876204 [Moellerella wisconsensis]
ATGAATGAAAGACAGGAAAATATGACTAAAACAGACTATCTGATGCGTTTAAGAAAATGCACGACTATTGAAACATTAGA
GCGTGTTATTGAAAAAAATAAATATGAGCTATCTGATGATGAACTCGAACTGTTTTTTTCCGCTGCTGACCATCGTCTAG
CAGAACTAACAATGAATAAACTGTATGACAAAATTCCAGCATCTGTCTGGAAATATGTTCGATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10333.77 Da        Isoelectric Point: 4.0944

>AT225125 WP_090202280.1 NZ_CP087202:c850880-850593 [Pseudomonas asplenii]
MQSVLSKMVVSVSELKKNPSAVLNGAGGEPVAVLNHNRVMGYMVPADVFEALMERLDDLELAQLARERIEANETPVQISL
DDLIAEAQADLEDGR

Download         Length: 288 bp

>AT225125 NZ_CP120978:2875565-2875933 [Moellerella wisconsensis]
ATGGATGAATATTCACCCAGATATTACGATACTGCTGAATTAAAGTATTTATGTGATAGCCTTAACAATGATGCGATATT
ATCGCTACATAAGACTAAAACGCATTGGATTAATGATTTAAGTTCACAGCAAAGTACGAATTTGAATGAGTTAATAGAGC
ATGTGGCTGCATTTTTTTGGAAATTTAAGATAAAATACCCTAGTGAACGCTTAGTCATCTCTCTAGTTGATGAATATCTT
GATGAAACTTATAATTTATTTGGTAGTCCATTAATCACATTAAATGAATTTTCAGATTGGCAAAAAATGAATACTCACTT
AATTGATGAATTAAATAACGATTTAAAGTGTTCAGTAGCCAAACTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References