Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2963079..2964335 Replicon chromosome
Accession NZ_CP087201
Organism Pseudomonas sp. B21-059

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LOY69_RS13630 Protein ID WP_265074741.1
Coordinates 2963763..2964335 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LOY69_RS13625 Protein ID WP_265074892.1
Coordinates 2963079..2963636 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY69_RS13600 (LOY69_13565) 2958387..2959007 - 621 WP_265074737.1 LysE family translocator -
LOY69_RS13605 (LOY69_13570) 2959248..2959835 - 588 WP_170004248.1 AidA/PixA family protein -
LOY69_RS13610 (LOY69_13575) 2960087..2960701 - 615 WP_265074738.1 alpha/beta hydrolase -
LOY69_RS13615 (LOY69_13580) 2960935..2962131 + 1197 WP_265074739.1 PrpF domain-containing protein -
LOY69_RS13620 (LOY69_13585) 2962548..2962889 - 342 WP_265074740.1 low molecular weight protein tyrosine phosphatase family protein -
LOY69_RS13625 (LOY69_13590) 2963079..2963636 + 558 WP_265074892.1 helix-turn-helix transcriptional regulator Antitoxin
LOY69_RS13630 (LOY69_13595) 2963763..2964335 + 573 WP_265074741.1 HD domain-containing protein Toxin
LOY69_RS13635 (LOY69_13600) 2964596..2966776 + 2181 WP_265074742.1 catalase/peroxidase HPI -
LOY69_RS13640 (LOY69_13605) 2966853..2967281 - 429 WP_265074743.1 hypothetical protein -
LOY69_RS13645 (LOY69_13610) 2967516..2968430 + 915 WP_265074744.1 SGNH/GDSL hydrolase family protein -
LOY69_RS13650 (LOY69_13615) 2968481..2968735 + 255 Protein_2686 IS66 family insertion sequence element accessory protein TnpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21573.27 Da        Isoelectric Point: 5.5862

>T225123 WP_265074741.1 NZ_CP087201:2963763-2964335 [Pseudomonas sp. B21-059]
MTPELLSGRLEFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGELDLLRVLKLCIVHDLGEAIHGDIP
AVAQAGHPHKSQQERDDLQFLARSLDAPARQRLLDLWDEYEGAASAEARTVKALDKLETLLQHTQGQNPADFDYRFNLGY
GRRYTDASPLFQALRQQIDIDTQRRLNAQG

Download         Length: 573 bp

>T225123 NZ_CP120978:2670270-2670521 [Moellerella wisconsensis]
ATGAAAGCGGTAAGCTACAGTGAAGCCAGACAGAATTTATCAACAACAATGATTCAAACAGTTGAAGATAGAGTACCAGT
ACTGATCACGCGCCAGAATGGCGAATCATGTGTACTGATGTCTCTCGATGAATATAACTCTCTCGAAGAGACGGCATACC
TAATGAGATCACCAAAAAATGCACGCAGACTTATGGACTCGATAGAAAGCCTAAAAGATGGAAAAGGGATGGAAAGGGAA
ATTATTAAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20353.26 Da        Isoelectric Point: 7.0307

>AT225123 WP_265074892.1 NZ_CP087201:2963079-2963636 [Pseudomonas sp. B21-059]
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGQQAMEPAERARLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSATRAGQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPPSVEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT225123 NZ_CP120978:2670518-2670772 [Moellerella wisconsensis]
GTGAAGCTAACATGGTCTGCCGAAGCATGGGAAGATTACTTGTACTGGCAAGAAACGGACAGAAAAACCGTAAAAAAGAT
AAATGAGCTCATTAAGAATGCCAGTAGAACACCATTTGAAGGAAAAGGTAAACCTGAACCTCTGAAACACAATCTTGCTG
GGTTCTGGTCACGAAGAATTACGGCGGAACATCGATTAGTCTATGCCGTTAGTAATGATTCCTTGCTAATAGCATCATGT
CGTTATCACTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References