Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1549080..1549593 Replicon chromosome
Accession NZ_CP087201
Organism Pseudomonas sp. B21-059

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY69_RS07010 Protein ID WP_110595048.1
Coordinates 1549080..1549364 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY69_RS07015 Protein ID WP_092320301.1
Coordinates 1549354..1549593 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY69_RS06990 (LOY69_06995) 1544891..1545673 - 783 WP_102878683.1 aldolase -
LOY69_RS06995 (LOY69_07000) 1545835..1546377 + 543 WP_110651880.1 XRE family transcriptional regulator -
LOY69_RS07000 (LOY69_07005) 1546703..1547722 - 1020 WP_265074878.1 DUF4917 family protein -
LOY69_RS07005 (LOY69_07010) 1547880..1549028 + 1149 WP_102878685.1 L-threonine dehydrogenase -
LOY69_RS07010 (LOY69_07015) 1549080..1549364 - 285 WP_110595048.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY69_RS07015 (LOY69_07020) 1549354..1549593 - 240 WP_092320301.1 ribbon-helix-helix protein, CopG family Antitoxin
LOY69_RS07020 (LOY69_07025) 1549794..1550531 + 738 WP_253083877.1 hypothetical protein -
LOY69_RS07025 (LOY69_07030) 1550542..1551273 + 732 WP_253163034.1 hypothetical protein -
LOY69_RS07030 (LOY69_07035) 1551277..1551693 + 417 WP_265074309.1 fosfomycin resistance glutathione transferase -
LOY69_RS07035 (LOY69_07040) 1551820..1552458 + 639 WP_102878689.1 LysE family translocator -
LOY69_RS07040 (LOY69_07045) 1552567..1553916 + 1350 WP_102878690.1 GGDEF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11040.72 Da        Isoelectric Point: 11.8691

>T225121 WP_110595048.1 NZ_CP087201:c1549364-1549080 [Pseudomonas sp. B21-059]
MRIEWLRSALNNLDAEARHIAQDDPRAAGEFVRALLISIEQLARFPSSGREGRLPGTREWVVPGWPYLIPYRVRGDRLQI
LRIFHTRRQPPARW

Download         Length: 285 bp

>T225121 NZ_CP120975:c323616-323305 [Moellerella wisconsensis]
ATGCACGTAATTTCAAGAGATCCTTTTAACCAGGCATCCAAGCGATTTCCTAACAGTGCTCAGGCGTTATCTGACGTATA
TCGAACACTTAAGCGCGATAGTTATCAGACACCCGATGAGCTTAAGAAGGTTTTCCCCAGCCTTGACCGAATGAAGTACA
GAGAGAAATGGTGGGTTATCGATATCAGTGGAAATGCGTTAAGAATGATGTTTTTCGCCGACTTTGACCGGGGAAAAATA
TTCGTGAAACACATAACGACCCACGCAGAGTACGATAAGTTGACAGATCACTACCGGAGAACAAAAGCATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8604.71 Da        Isoelectric Point: 4.3085

>AT225121 WP_092320301.1 NZ_CP087201:c1549593-1549354 [Pseudomonas sp. B21-059]
MSIMSLRLPDELAETLALLAKATGRSKSFLAVDALREYLAREAWQIEEIQKALNEADAGDFASAEEVAAIAGKWTDNAH

Download         Length: 240 bp

>AT225121 NZ_CP120975:c323308-322892 [Moellerella wisconsensis]
ATGATGTTTCAAGACGCCGTAAAAGCGGCACAAAACCTGGTAAATCTAGTCCCGTTACTGGGAGACAGCCATTCACGCCC
GGATTATGAAAAGGCCGTTCAGTTGGTGGAGCATCTTGTCGAGAACGACCCTGACAATCCGCTCATCGATATGATTTGCG
CAAAAATAGATGCGTATGAAAATGCCGCACCTGAATTTGCAGAGTTTAACCAACGTTTAGCAGAAAGTAATGATGGTGTG
GCAGCGTTAAGAACGCTGATGGATCAATACAACCTCAATACGACAGACTTTGGAAATGAGCTCGGTTCTCGTTCATACGT
CAGCCGTATCCTCAATGGGGAACGTGGATTAACCTTGGAGCACATCAAAAATCTGTCCAAACGCTTTGGTATTCCAGCCT
CAATATTTATTCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References