Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 722883..723479 Replicon chromosome
Accession NZ_CP087201
Organism Pseudomonas sp. B21-059

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LOY69_RS03210 Protein ID WP_123391220.1
Coordinates 723177..723479 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY69_RS03205 Protein ID WP_102881959.1
Coordinates 722883..723173 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY69_RS03185 (LOY69_03185) 719155..721287 - 2133 WP_110650898.1 TonB-dependent copper receptor -
LOY69_RS03190 (LOY69_03190) 721376..721822 - 447 WP_265074120.1 DUF2946 domain-containing protein -
LOY69_RS03195 (LOY69_03195) 721841..722320 - 480 WP_180988479.1 copper chaperone PCu(A)C -
LOY69_RS03200 (LOY69_03200) 722385..722783 - 399 WP_102881960.1 DUF2946 domain-containing protein -
LOY69_RS03205 (LOY69_03205) 722883..723173 - 291 WP_102881959.1 putative addiction module antidote protein Antitoxin
LOY69_RS03210 (LOY69_03210) 723177..723479 - 303 WP_123391220.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY69_RS03215 (LOY69_03215) 723662..724390 - 729 WP_110650887.1 cobalt-precorrin-6A reductase -
LOY69_RS03220 (LOY69_03220) 724387..725484 - 1098 WP_102862980.1 cobalt-precorrin-5B (C(1))-methyltransferase -
LOY69_RS03225 (LOY69_03225) 725578..726792 - 1215 WP_265074121.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
LOY69_RS03230 (LOY69_03230) 726894..728237 + 1344 WP_265074869.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-97)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11619.37 Da        Isoelectric Point: 10.6580

>T225120 WP_123391220.1 NZ_CP087201:c723479-723177 [Pseudomonas sp. B21-059]
MFVFEQTQAFTHWLLRLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVYEMRIHRGPGYRVYFSRRDTVIYLLLIGGDKG
TQRRDIQRARQLAHDLKSEG

Download         Length: 303 bp

>T225120 NZ_CP120975:c274950-274561 [Moellerella wisconsensis]
GTGGCGTTCTATAAAATCTCATCTTTTGTCCGAAGCACCAAAAAAATACCTATAACAGACAAACAGTTACTTGATGCTGC
TCATGAAGTTCAACAAGGACAATTTGAAGCTGATTTAGGCGGTGGAGTGATAAAAAAACGCCTTGCAATGAAAGGGCAAG
GCAAAAGTGGAAGTGTTAGGGTTATTATCTTTTTTAAGATAAACAATCATCTTTTTTTTGCAGATGGATGGACCAAAAAC
ACGGTCAATGCCAAAGGTACAAAAGAGATTGAAGATGATGAGTTGGAAACCTATAAAAAATTAGCCGCTGAGTTTCTGAA
CTTTGATGGAGAAATCATTAACAATTTAATTTCTAAAGGAATTCTGGAGGAAATTACTGATGAACAATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10429.01 Da        Isoelectric Point: 6.9783

>AT225120 WP_102881959.1 NZ_CP087201:c723173-722883 [Pseudomonas sp. B21-059]
MRTPVTRFDAAEYLKTPEDMVAYLDACFEEDAGDGKLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLHVSPA

Download         Length: 291 bp

>AT225120 NZ_CP120975:c274571-274242 [Moellerella wisconsensis]
ATGAACAATAAACTTAATAACATGCTTGAATTGGCTAAAGAGTTAAATGCAGCTGGTGCATCACCTGAAAGCCTGGTTAA
AGATATTGAAAGCACCATCCGTGCTCGTGAAATTAACGATAAAATAAAAGAAGTTTCAGCGATGAGCGGCTCTGAGATCA
AGATGTTGCGGACTAAATATTGTATGTCTCAATCTGTGCTCGCTCGTGCATTGGGAATGTCGAAAGAGAGCATATCCAAA
TGGGAGCGAGGAGAAAAGAAACCAAGCGGCCCTGCATTGAGGATGCTACGTATTCTTGAAAGCAAAGGCCCAGAAGTTTT
AGTGGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References