Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2340921..2341443 Replicon chromosome
Accession NZ_CP087200
Organism Pseudomonas viciae strain B21-062

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY66_RS10475 Protein ID WP_135844720.1
Coordinates 2341159..2341443 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY66_RS10470 Protein ID WP_135844719.1
Coordinates 2340921..2341169 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY66_RS10455 (LOY66_10445) 2337345..2338346 + 1002 WP_135844717.1 AAA family ATPase -
LOY66_RS10460 (LOY66_10450) 2338448..2339002 + 555 WP_256454388.1 VWA domain-containing protein -
LOY66_RS10465 (LOY66_10455) 2339208..2340854 + 1647 WP_256452549.1 phospholipase D-like domain-containing protein -
LOY66_RS10470 (LOY66_10460) 2340921..2341169 + 249 WP_135844719.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LOY66_RS10475 (LOY66_10465) 2341159..2341443 + 285 WP_135844720.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY66_RS10480 (LOY66_10470) 2341552..2341893 + 342 WP_265072894.1 hypothetical protein -
LOY66_RS10485 (LOY66_10475) 2342316..2343164 + 849 WP_135844722.1 transporter substrate-binding domain-containing protein -
LOY66_RS10490 (LOY66_10480) 2343219..2343881 + 663 WP_135844723.1 amino acid ABC transporter permease -
LOY66_RS10495 (LOY66_10485) 2343891..2344553 + 663 WP_135844724.1 amino acid ABC transporter permease -
LOY66_RS10500 (LOY66_10490) 2344550..2345356 + 807 WP_256452553.1 amino acid ABC transporter ATP-binding protein -
LOY66_RS10505 (LOY66_10495) 2345394..2345783 + 390 WP_135844726.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10946.63 Da        Isoelectric Point: 10.2243

>T225118 WP_135844720.1 NZ_CP087200:2341159-2341443 [Pseudomonas viciae]
MTYELEFSDKAWKEWQKLGATLRAQFKKKLEERLENPHVQADRLHGLGNAYKIKLRNAGYRLVYRVVDDLLVVTVIGVGK
RERGQVYDEAAAKR

Download         Length: 285 bp

>T225118 NZ_CP120975:c91932-91582 [Moellerella wisconsensis]
ATGTGGGAAATATTAACGAGAGATCTCTTTGATTCTTGGTTCGAAGAGCAAAATGAGGAAACTCAGATTGAAGTGTTGGC
AGTGTTAATGATTTTACGTGAGGATGGCCCCAATCTTGGACGCCCTCAAGTTGACACCCTGAAGGGCTCACAGTTTCCCA
ACATGAAGGAACTGCGAATTCAGGTTGGTGGTCATCCGATTAGAGCGTGTTTCGCATTTGACCCAATTCGTCGTGGCATT
GTGTTATGTGCCGGTGATAAGAAAGGAAAAGATGAAACCCGTTTCTACAAGAAATTAATCAAGATGGCCGATGCGGAATA
TGCAGCGCACTTATTAGAGCAGGAGAAATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8999.39 Da        Isoelectric Point: 4.4000

>AT225118 WP_135844719.1 NZ_CP087200:2340921-2341169 [Pseudomonas viciae]
MTHIVLSQVVASISELKKNPMGTVAAGGGLSVAILNRNEPAFYCVPAKEYEAMMDRLEDMELVALCRERENDSTIKVSLD
DL

Download         Length: 249 bp

>AT225118 NZ_CP120975:c91580-91281 [Moellerella wisconsensis]
ATGTCCACTTTAAATGAACTACTTGCAAAACAATCCCCCGAAACGCAGGCAAAAATTGAAGACCGAGCAGAAGAAATCCG
GCGTGAAATCACACTAGCTAAAATTCGTGAGGAACTGAAACTTTCTCAAACTGAGCTAGCTCAATCACTGGGCGTTTCGC
AACCTTCTATTGCTAAGCTTGAAAATGTTGATAACGATCCGAAGCTTTCAACTCTGAAGCGCTACATTAAAGCTTTAGGC
GGTGAACTTTCTATCGATGTAACGTTACCGAATGGTAAGAGAATTGGATTGCATCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References