Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
| Location | 1481389..1483082 | Replicon | chromosome |
| Accession | NZ_CP087199 | ||
| Organism | Pseudomonas sp. B21-009 | ||
Toxin (Protein)
| Gene name | doc | Uniprot ID | - |
| Locus tag | LOY34_RS06830 | Protein ID | WP_195885904.1 |
| Coordinates | 1482213..1483082 (-) | Length | 290 a.a. |
Antitoxin (Protein)
| Gene name | phd | Uniprot ID | A0A1H1EW67 |
| Locus tag | LOY34_RS06825 | Protein ID | WP_045193445.1 |
| Coordinates | 1481389..1482216 (-) | Length | 276 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOY34_RS06805 (LOY34_06790) | 1476597..1478087 | - | 1491 | WP_195885900.1 | aldehyde dehydrogenase | - |
| LOY34_RS06810 (LOY34_06795) | 1478098..1478901 | - | 804 | WP_195885901.1 | aspartate dehydrogenase | - |
| LOY34_RS06815 (LOY34_06800) | 1478912..1480594 | - | 1683 | WP_258664432.1 | thiamine pyrophosphate-binding protein | - |
| LOY34_RS06820 (LOY34_06805) | 1480587..1481387 | - | 801 | WP_195885903.1 | SDR family oxidoreductase | - |
| LOY34_RS06825 (LOY34_06810) | 1481389..1482216 | - | 828 | WP_045193445.1 | IclR family transcriptional regulator | Antitoxin |
| LOY34_RS06830 (LOY34_06815) | 1482213..1483082 | - | 870 | WP_195885904.1 | alpha/beta fold hydrolase | Toxin |
| LOY34_RS06835 (LOY34_06820) | 1483087..1483626 | - | 540 | WP_093386119.1 | cupin domain-containing protein | - |
| LOY34_RS06840 (LOY34_06825) | 1483641..1484405 | - | 765 | WP_195885963.1 | SDR family oxidoreductase | - |
| LOY34_RS06845 (LOY34_06830) | 1484405..1485181 | - | 777 | WP_045193442.1 | ABC transporter permease | - |
| LOY34_RS06850 (LOY34_06835) | 1485211..1486209 | - | 999 | WP_195885905.1 | ABC transporter substrate-binding protein | - |
| LOY34_RS06855 (LOY34_06840) | 1486249..1487085 | - | 837 | WP_045193440.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 290 a.a. Molecular weight: 30715.12 Da Isoelectric Point: 7.4853
>T225113 WP_195885904.1 NZ_CP087199:c1483082-1482213 [Pseudomonas sp. B21-009]
MLHATDHSLAGLAAQLQQRFPQRLVQLASGAQAIREAGQGPAIVLLHGIGSGAASWLQVALQLSQQARVIAWDAPGYGDS
SPLANPAPQAVDYARRLRHLLDALQIADCLLVGHSLGALSAAALAQQQPQRVRRLVLISPARGYGDPARAEQAQQVRRQR
LHNLEQLGIAQMAHQRSAHMLSPAASSEARAWVQWNMARLLPQGYRQAIELLCGDDLLRYAALAVPCEVHCGAADSITRP
EDCQALAKALGAAFALIAEAGHASPIEQPEAVATLLARALEESLTGTAL
MLHATDHSLAGLAAQLQQRFPQRLVQLASGAQAIREAGQGPAIVLLHGIGSGAASWLQVALQLSQQARVIAWDAPGYGDS
SPLANPAPQAVDYARRLRHLLDALQIADCLLVGHSLGALSAAALAQQQPQRVRRLVLISPARGYGDPARAEQAQQVRRQR
LHNLEQLGIAQMAHQRSAHMLSPAASSEARAWVQWNMARLLPQGYRQAIELLCGDDLLRYAALAVPCEVHCGAADSITRP
EDCQALAKALGAAFALIAEAGHASPIEQPEAVATLLARALEESLTGTAL
Download Length: 870 bp
>T225113 NZ_CP120974:c2471119-2470709 [Moellerella wisconsensis]
GTGGTCCTGTGGAAATCTAATTTATCCATATCATGGATGGCTCAGCTTTTTTCTACCTGTGTACATTGTGTCCTGGGGCT
AGTGTTATTACTGGCTCCGTGGCCGACAGGTAACTCTATTATTTGGCTTCCTTTATTAATGGTGACTATTGCGAGTTGGG
CAAAAAGTCAAAAAAACATTAATAAATACAAAGGAATAATTGTTCTTACTAATGGGAATAAAGTCCAATGGAAGAAAAAT
GAATGGAGTATTATCACTCCTCCATGGTGTACTCGCTTTGGTATTTTATTAACGTTAAGTGCATTACAAGGTAAACCTAG
AAAAATAAAATTATGGATTGCAGCTGATGCAATATCAGAAGACGATTGGCGAAATTTAAATCAGTTATTATTACAATATC
CTGATATATAA
GTGGTCCTGTGGAAATCTAATTTATCCATATCATGGATGGCTCAGCTTTTTTCTACCTGTGTACATTGTGTCCTGGGGCT
AGTGTTATTACTGGCTCCGTGGCCGACAGGTAACTCTATTATTTGGCTTCCTTTATTAATGGTGACTATTGCGAGTTGGG
CAAAAAGTCAAAAAAACATTAATAAATACAAAGGAATAATTGTTCTTACTAATGGGAATAAAGTCCAATGGAAGAAAAAT
GAATGGAGTATTATCACTCCTCCATGGTGTACTCGCTTTGGTATTTTATTAACGTTAAGTGCATTACAAGGTAAACCTAG
AAAAATAAAATTATGGATTGCAGCTGATGCAATATCAGAAGACGATTGGCGAAATTTAAATCAGTTATTATTACAATATC
CTGATATATAA
Antitoxin
Download Length: 276 a.a. Molecular weight: 30416.81 Da Isoelectric Point: 6.3865
>AT225113 WP_045193445.1 NZ_CP087199:c1482216-1481389 [Pseudomonas sp. B21-009]
MNDSDLLKDNQDKYIVPGLERGLLLLCEFSRQNRTLTAPELARRLELPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDHLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVLELFDLVQSDRQRGYVSGEGFFESSISTIAAPVRDHSGRVVAAMGVTIPTVQVAHINF
DGLLGHVRGSADELSRLLNYTPNAGSGRVTALMRD
MNDSDLLKDNQDKYIVPGLERGLLLLCEFSRQNRTLTAPELARRLELPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDHLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVLELFDLVQSDRQRGYVSGEGFFESSISTIAAPVRDHSGRVVAAMGVTIPTVQVAHINF
DGLLGHVRGSADELSRLLNYTPNAGSGRVTALMRD
Download Length: 828 bp
>AT225113 NZ_CP120974:c2471366-2471100 [Moellerella wisconsensis]
ATGGATATTGATAATAAAGCGCGGATCCACTGGGCATGTCGTCGAGGAATGCGAGAACTAGATATTTCAATCATGCCTTT
TTTTGAACATGAGTATGATGGATTAAACGATAATGAAAAACACCAGTTTATTCGTTTGCTGGAGTGTGCAGATCCCGATC
TGTTCAATTGGTTGATGAACCATGGTCGTCCTGACGATGATGAGCTTTATCATATGATTAAACTAATTCAACAAAGAAAT
AAAGACCGTGGTCCTGTGGAAATCTAA
ATGGATATTGATAATAAAGCGCGGATCCACTGGGCATGTCGTCGAGGAATGCGAGAACTAGATATTTCAATCATGCCTTT
TTTTGAACATGAGTATGATGGATTAAACGATAATGAAAAACACCAGTTTATTCGTTTGCTGGAGTGTGCAGATCCCGATC
TGTTCAATTGGTTGATGAACCATGGTCGTCCTGACGATGATGAGCTTTATCATATGATTAAACTAATTCAACAAAGAAAT
AAAGACCGTGGTCCTGTGGAAATCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|