Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA-HicB |
Location | 251290..251933 | Replicon | chromosome |
Accession | NZ_CP087194 | ||
Organism | Pseudomonas sp. B21-017 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | LOY28_RS01085 | Protein ID | WP_018929327.1 |
Coordinates | 251290..251472 (+) | Length | 61 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | LOY28_RS01090 | Protein ID | WP_008005174.1 |
Coordinates | 251469..251933 (+) | Length | 155 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LOY28_RS01065 (LOY28_01065) | 247112..249067 | + | 1956 | WP_204124005.1 | choline transporter BetT | - |
LOY28_RS01070 (LOY28_01070) | 249082..249342 | - | 261 | WP_018929330.1 | hypothetical protein | - |
LOY28_RS01075 (LOY28_01075) | 249405..250145 | - | 741 | WP_019651514.1 | SDR family oxidoreductase | - |
LOY28_RS01080 (LOY28_01080) | 250271..251161 | + | 891 | WP_018929328.1 | LysR family transcriptional regulator | - |
LOY28_RS01085 (LOY28_01085) | 251290..251472 | + | 183 | WP_018929327.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
LOY28_RS01090 (LOY28_01090) | 251469..251933 | + | 465 | WP_008005174.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
LOY28_RS01095 (LOY28_01095) | 252100..253137 | + | 1038 | WP_018929326.1 | L-glyceraldehyde 3-phosphate reductase | - |
LOY28_RS01100 (LOY28_01100) | 253191..254033 | - | 843 | WP_258612951.1 | taurine dioxygenase | - |
LOY28_RS01105 (LOY28_01105) | 254073..254921 | - | 849 | WP_018929324.1 | taurine ABC transporter permease TauC | - |
LOY28_RS01110 (LOY28_01110) | 254918..255712 | - | 795 | WP_018929323.1 | taurine ABC transporter ATP-binding subunit | - |
LOY28_RS01115 (LOY28_01115) | 255729..256706 | - | 978 | WP_258612952.1 | taurine ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6873.01 Da Isoelectric Point: 10.3203
>T225093 WP_018929327.1 NZ_CP087194:251290-251472 [Pseudomonas sp. B21-017]
MRSREMIRMIEEDGWYLVAVKGSHHQYKHPCKSGRVTIKHPDSDLPKGTINSILKQAGLK
MRSREMIRMIEEDGWYLVAVKGSHHQYKHPCKSGRVTIKHPDSDLPKGTINSILKQAGLK
Download Length: 183 bp
>T225093 NZ_CP120956:5850338-5850718 [Delftia tsuruhatensis]
ATGAATCCCGTTCTGGTCGATACCTCGGTCTGGATCGATCACTTCAGGCAGGGCAATCCTCACCTGGCGCAGTTGCTGCA
GCAAGACATGGCGCTCATGCATCCCCTGGTGCTGGGTGAACTGGCTTGCGGCACGCCACCGGCACGCGCACGCACGCTCG
CGGACCTTCAGCGGCTCAAGCCTGCCCGACAGGCCAGCATGCGCGAAGTGCTGGCCTTGATAGAGCGCGAGCAACTCTTT
GGTCTGGGCTGCGGTCTGGTGGACATCACGCTCCTGGCCTCGGCACTCATGTCTTCAGGCGCCAGCCTGTGGTCGCTGGA
CAAACGCCTGCACGCGCTGGCCCAGCGGTTTGGCATTGCCTGCCGGAGCGTCTTGCCGTAG
ATGAATCCCGTTCTGGTCGATACCTCGGTCTGGATCGATCACTTCAGGCAGGGCAATCCTCACCTGGCGCAGTTGCTGCA
GCAAGACATGGCGCTCATGCATCCCCTGGTGCTGGGTGAACTGGCTTGCGGCACGCCACCGGCACGCGCACGCACGCTCG
CGGACCTTCAGCGGCTCAAGCCTGCCCGACAGGCCAGCATGCGCGAAGTGCTGGCCTTGATAGAGCGCGAGCAACTCTTT
GGTCTGGGCTGCGGTCTGGTGGACATCACGCTCCTGGCCTCGGCACTCATGTCTTCAGGCGCCAGCCTGTGGTCGCTGGA
CAAACGCCTGCACGCGCTGGCCCAGCGGTTTGGCATTGCCTGCCGGAGCGTCTTGCCGTAG
Antitoxin
Download Length: 155 a.a. Molecular weight: 16808.81 Da Isoelectric Point: 4.2692
>AT225093 WP_008005174.1 NZ_CP087194:251469-251933 [Pseudomonas sp. B21-017]
MRPDIGNESLEGATSQEGLIEMKFPVVLHKDADSEYGVIIPDVPGCFSAGATVAQAFENVKEALALHYEGLVADGDPLPQ
VREIDAHLDNPDYAGGVWGVVEFDITPYFGKSVRFNATLPEQLLERIDQTVRRDQRYSSRSGFLAAAALRELSA
MRPDIGNESLEGATSQEGLIEMKFPVVLHKDADSEYGVIIPDVPGCFSAGATVAQAFENVKEALALHYEGLVADGDPLPQ
VREIDAHLDNPDYAGGVWGVVEFDITPYFGKSVRFNATLPEQLLERIDQTVRRDQRYSSRSGFLAAAALRELSA
Download Length: 465 bp
>AT225093 NZ_CP120956:5850138-5850341 [Delftia tsuruhatensis]
ATGAGAACCACGGTCACCATCGACGACGCCTTGTACGAGGAAGCGCTGGAGCTGGCGGAGCCAGAAATGGACAAGGCCGA
CCTGTTTCGCGAAGCCATCAAGACTTTCGTGAGAGTGCAGGCGGCCAAGCGTCTGGCCGCGCTGGGAGGCTCCGCACCGG
ACATGCGGGAGATTCCCCGTCGCCCACAGGGCATCGAGCCATGA
ATGAGAACCACGGTCACCATCGACGACGCCTTGTACGAGGAAGCGCTGGAGCTGGCGGAGCCAGAAATGGACAAGGCCGA
CCTGTTTCGCGAAGCCATCAAGACTTTCGTGAGAGTGCAGGCGGCCAAGCGTCTGGCCGCGCTGGGAGGCTCCGCACCGG
ACATGCGGGAGATTCCCCGTCGCCCACAGGGCATCGAGCCATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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