Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relE-yefM/YoeB-YefM |
| Location | 1077255..1077760 | Replicon | chromosome |
| Accession | NZ_CP087193 | ||
| Organism | Pseudomonas sp. B21-019 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | J2N6H1 |
| Locus tag | LOY36_RS04735 | Protein ID | WP_007940443.1 |
| Coordinates | 1077255..1077509 (-) | Length | 85 a.a. |
Antitoxin (Protein)
| Gene name | yefM | Uniprot ID | - |
| Locus tag | LOY36_RS04740 | Protein ID | WP_007940444.1 |
| Coordinates | 1077506..1077760 (-) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOY36_RS04715 (LOY36_04715) | 1073244..1073960 | + | 717 | WP_258672420.1 | peptide-methionine (S)-S-oxide reductase MsrA | - |
| LOY36_RS04720 (LOY36_04720) | 1073976..1074989 | - | 1014 | WP_258672421.1 | sensor domain-containing diguanylate cyclase | - |
| LOY36_RS04725 (LOY36_04725) | 1075065..1075970 | - | 906 | WP_138866847.1 | LysR family transcriptional regulator | - |
| LOY36_RS04730 (LOY36_04730) | 1076073..1077248 | + | 1176 | WP_258672422.1 | aspartate aminotransferase family protein | - |
| LOY36_RS04735 (LOY36_04735) | 1077255..1077509 | - | 255 | WP_007940443.1 | Txe/YoeB family addiction module toxin | Toxin |
| LOY36_RS04740 (LOY36_04740) | 1077506..1077760 | - | 255 | WP_007940444.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| LOY36_RS04745 (LOY36_04745) | 1077989..1078516 | - | 528 | WP_258672423.1 | adenylate kinase | - |
| LOY36_RS04750 (LOY36_04750) | 1078533..1080470 | - | 1938 | WP_258672424.1 | alkaline phosphatase D family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9997.52 Da Isoelectric Point: 8.0472
>T225089 WP_007940443.1 NZ_CP087193:c1077509-1077255 [Pseudomonas sp. B21-019]
MNIEFTPEGWDDYLWFQQNDKAGLKRINLLIKAILREPFEGLGKPEPLKHNLSGLWSRRITSEHRLVYAIENGEVRIVLC
RYHY
MNIEFTPEGWDDYLWFQQNDKAGLKRINLLIKAILREPFEGLGKPEPLKHNLSGLWSRRITSEHRLVYAIENGEVRIVLC
RYHY
Download Length: 255 bp
>T225089 NZ_CP120956:c78380-77535 [Delftia tsuruhatensis]
ATGAGCCGCGATATCGCAGCCTCGATCCGTGCACGTTTGAAGCAATGCGCGGACGCCCGCAGGCAGGACTTCAACCTCAC
GCTCACCTACTATGGCCTGGAGCGCCTGCTGTACCGCCTGTCCATCTCGCCCCATGCGGACAGCTATCTGCTCAAGGGCG
CACTGCTGTTTGCCATCTGGTACGAGCAGCCGCACAGGCCGACCCGCGACGCCGATCTGCTGGGCTTTGGCCTGGACGAC
GTTGACTCGGCGGTGAGCGCTTTCCGCGAGATCTGCCGGATTGCCGTGGACGACGGCATTGCCTTCGATGCCGCGTCGGT
GCGTGGAACCACCATCCGCAAGGAAGCCGGCTATGGCGGAGTACGGATTGACCTGCGCGCCACGCTGGACGGTGCACGCA
TCACGCTGCAGGTGGACATAGGCTTCGGCGATGCCGTGACACCATCGCCACAAGCCATCCGCTACCCCGTGCTGCTCGAC
GGCCTGCCCGCACCGCAACTGCGCAGCTACCCCAAGTACACCGTGGTGGCCGAAAAACTCCACGCGATATGCCTGCTGGG
CATGGCCAATACCCGGATGAAGGACTACTTCGATCTCTGGGTATTGATGACCGAAGGCACGCTGGACCCTGCCGAACTGC
GGCGCGCCATGGCAGCGACCTTCGAGCGCCGCCAACTCGCGCTGCCCGCAGGCCTGCCAGCCGGATTGAGCGATGGCTTC
AGCAGCGATGCGGCCAAGCAGGCGCAGTGGGCCGCCTTCCTGAAGAAGAACCGGCTTGAAGCGCTGGAGCTGGCCCCTGT
CGTGGCAAGGCTGCGAGAGGAATTCCAGCAATGCGGCATCTTCTGA
ATGAGCCGCGATATCGCAGCCTCGATCCGTGCACGTTTGAAGCAATGCGCGGACGCCCGCAGGCAGGACTTCAACCTCAC
GCTCACCTACTATGGCCTGGAGCGCCTGCTGTACCGCCTGTCCATCTCGCCCCATGCGGACAGCTATCTGCTCAAGGGCG
CACTGCTGTTTGCCATCTGGTACGAGCAGCCGCACAGGCCGACCCGCGACGCCGATCTGCTGGGCTTTGGCCTGGACGAC
GTTGACTCGGCGGTGAGCGCTTTCCGCGAGATCTGCCGGATTGCCGTGGACGACGGCATTGCCTTCGATGCCGCGTCGGT
GCGTGGAACCACCATCCGCAAGGAAGCCGGCTATGGCGGAGTACGGATTGACCTGCGCGCCACGCTGGACGGTGCACGCA
TCACGCTGCAGGTGGACATAGGCTTCGGCGATGCCGTGACACCATCGCCACAAGCCATCCGCTACCCCGTGCTGCTCGAC
GGCCTGCCCGCACCGCAACTGCGCAGCTACCCCAAGTACACCGTGGTGGCCGAAAAACTCCACGCGATATGCCTGCTGGG
CATGGCCAATACCCGGATGAAGGACTACTTCGATCTCTGGGTATTGATGACCGAAGGCACGCTGGACCCTGCCGAACTGC
GGCGCGCCATGGCAGCGACCTTCGAGCGCCGCCAACTCGCGCTGCCCGCAGGCCTGCCAGCCGGATTGAGCGATGGCTTC
AGCAGCGATGCGGCCAAGCAGGCGCAGTGGGCCGCCTTCCTGAAGAAGAACCGGCTTGAAGCGCTGGAGCTGGCCCCTGT
CGTGGCAAGGCTGCGAGAGGAATTCCAGCAATGCGGCATCTTCTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9500.94 Da Isoelectric Point: 8.5163
>AT225089 WP_007940444.1 NZ_CP087193:c1077760-1077506 [Pseudomonas sp. B21-019]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGNLRAGKTKVRQ
LIEE
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGNLRAGKTKVRQ
LIEE
Download Length: 255 bp
>AT225089 NZ_CP120956:c78991-78377 [Delftia tsuruhatensis]
ATGCCCGCTCCTGGCTCCGCGCTCGAACAAGCCGTTCTGGCACTGGCCGAACAACGGCCGCTGCTGCGCGCACGCGACCT
TGCCGCGCTTGGCCTGCCGACCATGGCGCTGAGCCGGCTGGTCGCGGCAGGCCGCCTTGAACGCGTTGCACGCGGCCTGT
ACAGCCTGCCGGGCCGGCCGCTCAGCGAGCACCGCTCGCTGGCGGAAGTGGCCCTGCGCGTACCGCAAGGGGTGGTCTGC
CTGCTGTCCGCGCTGCGGGTCCACGGCATAGGAACGCAGGCGCCCTTCGAGGTGTGGATGGCCATTCCCCATCACTCGCC
CACGCCCCGCATAGACCAGCCTGCATTGCGCGCCATCCGCATGTCCGGTGCGGCACTGTCCGAAGGCGTGGAAACCCTGC
AGATCGATGGCGTCGGTGTCGCCGTCTTCAACGCATCGAAGACCGTGGCCGATTGCTTCAAGTACCGCAACAAGATCGGC
CTGGATGTGGCGCTGGAAGCACTGCGCGACGGATGGGCACAACGCAAGCTGACGGCCGACGCGCTCTGGCACTACGCAGC
CATCGACCGCGTCAGCAATGTGATGCGCCCCTACCTTGAAAGCATCGCCGCATGA
ATGCCCGCTCCTGGCTCCGCGCTCGAACAAGCCGTTCTGGCACTGGCCGAACAACGGCCGCTGCTGCGCGCACGCGACCT
TGCCGCGCTTGGCCTGCCGACCATGGCGCTGAGCCGGCTGGTCGCGGCAGGCCGCCTTGAACGCGTTGCACGCGGCCTGT
ACAGCCTGCCGGGCCGGCCGCTCAGCGAGCACCGCTCGCTGGCGGAAGTGGCCCTGCGCGTACCGCAAGGGGTGGTCTGC
CTGCTGTCCGCGCTGCGGGTCCACGGCATAGGAACGCAGGCGCCCTTCGAGGTGTGGATGGCCATTCCCCATCACTCGCC
CACGCCCCGCATAGACCAGCCTGCATTGCGCGCCATCCGCATGTCCGGTGCGGCACTGTCCGAAGGCGTGGAAACCCTGC
AGATCGATGGCGTCGGTGTCGCCGTCTTCAACGCATCGAAGACCGTGGCCGATTGCTTCAAGTACCGCAACAAGATCGGC
CTGGATGTGGCGCTGGAAGCACTGCGCGACGGATGGGCACAACGCAAGCTGACGGCCGACGCGCTCTGGCACTACGCAGC
CATCGACCGCGTCAGCAATGTGATGCGCCCCTACCTTGAAAGCATCGCCGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|