Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 946698..947217 Replicon chromosome
Accession NZ_CP087190
Organism Pseudomonas sp. B21-023

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY42_RS04360 Protein ID WP_258599887.1
Coordinates 946698..946988 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY42_RS04365 Protein ID WP_203648016.1
Coordinates 946978..947217 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY42_RS04345 (LOY42_04350) 945170..945310 + 141 WP_258599885.1 hypothetical protein -
LOY42_RS04350 (LOY42_04355) 945303..945533 + 231 WP_102682137.1 hypothetical protein -
LOY42_RS04355 (LOY42_04360) 945679..946331 - 653 Protein_847 hypothetical protein -
LOY42_RS04360 (LOY42_04365) 946698..946988 - 291 WP_258599887.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY42_RS04365 (LOY42_04370) 946978..947217 - 240 WP_203648016.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LOY42_RS04370 (LOY42_04375) 947309..948796 - 1488 WP_258599889.1 methylenetetrahydrofolate reductase C-terminal domain-containing protein -
LOY42_RS04375 (LOY42_04380) 949098..951401 + 2304 WP_258599891.1 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
LOY42_RS04380 (LOY42_04385) 951469..951987 + 519 WP_258599893.1 histidine phosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 924805..947217 22412


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11392.25 Da        Isoelectric Point: 10.2588

>T225084 WP_258599887.1 NZ_CP087190:c946988-946698 [Pseudomonas sp. B21-023]
MTYNLDFDARALKEWQKLGDTIRQQLKKKLATVLLNPRIEANRLHGFPDCYKIKLRSSGYRLVYQVIDHQIVVFVVAVDK
RERDQVYRKAAERLTE

Download         Length: 291 bp

>T225084 NZ_CP120948:2366457-2366795 [Burkholderia contaminans]
ATGGTTGACATACTGCAATCCATGCCCTACAGTGCGCCTACGTTCAGCATCCGGACCACCGGCGTCTTCGACACCTGGTT
TGCCGGCCTGCAGGATCGCGTCGCGAAGCGCCGCATCCAGGCACGCATCGACCGCCTCTCGATGGGCAATCCGGGCGACT
GGAAGTCCGCCGGCTCGCCGGTCGTCGAGATGCGGATCGACCACGGCCCGGGCTATCGCGTCTACTACGTCCGGCGCGGA
ACGATCTGGGTCATCCTGCTCTGCGGCGGCGATAAATCGTCGCAACAGGCCGACATCCGCGCCGCGCACGCGATGCTCGC
GCATCTCGACATGGAGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9034.45 Da        Isoelectric Point: 4.8146

>AT225084 WP_203648016.1 NZ_CP087190:c947217-946978 [Pseudomonas sp. B21-023]
MASINVRIDDDLKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEEDEALLATVRERLAAPQRVRVTLDDL

Download         Length: 240 bp

>AT225084 NZ_CP120948:2366799-2367098 [Burkholderia contaminans]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGATCATCTGAAAACCGAAGACGACATGGCCGACTACTTCGAAGC
GTGCCTGCAGGAAGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGTGCACGCGGCATGTCGC
AGGTCGCGCGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAACCCCAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAACTGCACGGCTCGAAAGCGCACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References