225078

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1011242..1011780 Replicon chromosome
Accession NZ_CP087189
Organism Pseudomonas protegens strain B21-024

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY29_RS04450 Protein ID WP_072443006.1
Coordinates 1011502..1011780 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U9L9U0
Locus tag LOY29_RS04445 Protein ID WP_047283908.1
Coordinates 1011242..1011505 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY29_RS04430 (LOY29_04430) 1007202..1009508 - 2307 WP_072443001.1 TonB-dependent siderophore receptor -
LOY29_RS04435 (LOY29_04435) 1009717..1010397 + 681 WP_072443003.1 Fe2+-dependent dioxygenase -
LOY29_RS04440 (LOY29_04440) 1010401..1011186 + 786 WP_065364618.1 tetratricopeptide repeat protein -
LOY29_RS04445 (LOY29_04445) 1011242..1011505 + 264 WP_047283908.1 ribbon-helix-helix domain-containing protein Antitoxin
LOY29_RS04450 (LOY29_04450) 1011502..1011780 + 279 WP_072443006.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY29_RS04455 (LOY29_04455) 1011851..1013014 - 1164 WP_015634137.1 type III PLP-dependent enzyme -
LOY29_RS04460 (LOY29_04460) 1013693..1014850 - 1158 WP_015634138.1 ABC transporter ATP-binding protein -
LOY29_RS04465 (LOY29_04465) 1014847..1015500 - 654 WP_011059225.1 ABC transporter permease -
LOY29_RS04470 (LOY29_04470) 1015513..1016406 - 894 WP_011059226.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10793.48 Da        Isoelectric Point: 10.6604

>T225078 WP_072443006.1 NZ_CP087189:1011502-1011780 [Pseudomonas protegens]
MRQLKWTSKALSDLARLFEFLAQANRSTAARTVQSLVQAPDALLSNPRLGEQLEEFKPRDVRRLLVGHYEMRYEIQGMAL
SILRIWHVREDR

Download         Length: 279 bp

>T225078 NZ_CP120947:1929675-1929836 [Burkholderia contaminans]
GTGACCACGCTCTACATGCTCGATACGAGCATCTGTTCGTTCATCATGCGCGAGCGGCCGCCCGTGGTGCTGTCCCGGTT
GCAATCGTGCGTCAATGCGCAGCACCGGATCGTCGTCTCGGCAATTACCTATGCCGAAATGCGATTCGGCGCGGCCGGCT
AG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9676.08 Da        Isoelectric Point: 5.6706

>AT225078 WP_047283908.1 NZ_CP087189:1011242-1011505 [Pseudomonas protegens]
MPATKVLTAHIPLDLADKVDQLASRLERSRAWVVKQALVAWVDQEEERRRLTLEALADVDAGRVVDHQSVLAWAQSLSGD
NPLPLPK

Download         Length: 264 bp

>AT225078 NZ_CP120947:1929412-1929678 [Burkholderia contaminans]
ATGCGCACCGTTTCCATTTTCAAGAATGCTCGTAACCAGGCAATCCGCATCCCGAAGGACATGGAGTTCGAGGGGGTGAC
CGAACTCGAGATTCGCCGCGAGGGCGACACGCTGCTGCTGCGGCCGGTGCGGCCCACATGTCTCTCGTTCGCGAGCGAAC
CGCCGGCCGACGCCGACTTCCTCGCCGAACGCCCGGCCGTCATCGAGCCCGGCCGCTTCGACCTGTCCGACGGTGGCGGC
GCCGCACCGACGGAGTCCGGCCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U9L9U0

References