Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 757658..758254 Replicon chromosome
Accession NZ_CP087189
Organism Pseudomonas protegens strain B21-024

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY29_RS03320 Protein ID WP_258611432.1
Coordinates 757952..758254 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY29_RS03315 Protein ID WP_258611431.1
Coordinates 757658..757948 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY29_RS03295 (LOY29_03295) 753928..756060 - 2133 WP_258611430.1 TonB-dependent copper receptor -
LOY29_RS03300 (LOY29_03300) 756149..756559 - 411 WP_011059017.1 DUF2946 domain-containing protein -
LOY29_RS03305 (LOY29_03305) 756615..757109 - 495 WP_011059018.1 copper chaperone PCu(A)C -
LOY29_RS03310 (LOY29_03310) 757159..757557 - 399 WP_011059019.1 DUF2946 domain-containing protein -
LOY29_RS03315 (LOY29_03315) 757658..757948 - 291 WP_258611431.1 putative addiction module antidote protein Antitoxin
LOY29_RS03320 (LOY29_03320) 757952..758254 - 303 WP_258611432.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY29_RS03325 (LOY29_03325) 758438..759166 - 729 WP_258611433.1 cobalt-precorrin-6A reductase -
LOY29_RS03330 (LOY29_03330) 759163..760260 - 1098 WP_258611434.1 cobalt-precorrin-5B (C(1))-methyltransferase -
LOY29_RS03335 (LOY29_03335) 760354..761568 - 1215 WP_011059024.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
LOY29_RS03340 (LOY29_03340) 761707..763020 + 1314 WP_258611435.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-97)

Antitoxin

Uncharacterized protein HI1420

(6-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11410.16 Da        Isoelectric Point: 10.0056

>T225077 WP_258611432.1 NZ_CP087189:c758254-757952 [Pseudomonas protegens]
MFVFEQTPEFSRWLLNLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVHEIRIHRGPGYLVYFSHRGKVIYLLLIGGDKA
TQNRDIQRARQLACDLKSEG

Download         Length: 303 bp

>T225077 NZ_CP120947:178486-178887 [Burkholderia contaminans]
ATGCCGCGCTACATGCTCGACACCAACATGTGCATCTACCTGATGAAGAATCAGCCGGAGCAGGTTGCGAGACGGTTTGC
GCAGTGCTACACGGGGGACGTCGTGATGTCGGCGATCACGTACGCCGAGCTCGAGTACGGCGTCGCGGCGTGCGCGAGCC
CTGCGCGGGAGCGCGGCAATCTTGCCGCGCTGATCGACGACATTCCCGTTGCGCCGTTCGACGTCGCGGCCGCGCAAGCG
TATGGCCCGGTCCGCGAGGCAACCCGGGAGCGGAAGAAGGATCACCTCGACAAGCTGATCGCCGCGCATGCGGTGTCGCT
CGATGTCGTACTCGTGACCAACAACGAGCGGGATTTCGTGAGCTATCCGGGACTGCGGCTGGAGAACTGGCTGGACGATT
GA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10419.95 Da        Isoelectric Point: 5.0939

>AT225077 WP_258611431.1 NZ_CP087189:c757948-757658 [Pseudomonas protegens]
MRPPVTRFDAAEYLKTPEDMVAYLDACFEEDTGDGVLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKINVSNA

Download         Length: 291 bp

>AT225077 NZ_CP120947:178250-178486 [Burkholderia contaminans]
ATGCATACGACGAGGGTATTTCGGAACGGCAACTCGCAGGCCGTGCGAATTCCTGCCGACCTTGCCTATGAACGCAGCGA
TATCGAACTGGAAATCGAGCGCATTGGTGACGAAATCCGCATTCGGCCGGCGCGGCGGCCGTTGACCCGCGTCCTTGAGA
AATTCGCTAAATTCGGGCCGGATTTCATGGCGGATGGGCGCGGTGACCACGAGCAGGCCGATCGCGAGGGTTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References