225076

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 180079..180595 Replicon chromosome
Accession NZ_CP087189
Organism Pseudomonas protegens strain B21-024

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY29_RS00790 Protein ID WP_258611350.1
Coordinates 180314..180595 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q4KKD3
Locus tag LOY29_RS00785 Protein ID WP_011058534.1
Coordinates 180079..180324 (+) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY29_RS00770 (LOY29_00770) 177573..179183 + 1611 WP_258611349.1 glycosyltransferase family 39 protein -
LOY29_RS00775 (LOY29_00775) 179293..179754 + 462 WP_011058532.1 YbaK/EbsC family protein -
LOY29_RS00780 (LOY29_00780) 179769..180014 + 246 WP_011058533.1 DUF2789 domain-containing protein -
LOY29_RS00785 (LOY29_00785) 180079..180324 + 246 WP_011058534.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LOY29_RS00790 (LOY29_00790) 180314..180595 + 282 WP_258611350.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY29_RS00795 (LOY29_00795) 180738..181166 + 429 WP_011058536.1 winged helix DNA-binding protein -
LOY29_RS00800 (LOY29_00800) 181163..183250 + 2088 WP_258611351.1 FUSC family protein -
LOY29_RS00805 (LOY29_00805) 183247..183456 + 210 WP_011058538.1 DUF1656 domain-containing protein -
LOY29_RS00810 (LOY29_00810) 183453..184343 + 891 WP_011058539.1 HlyD family secretion protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10859.77 Da        Isoelectric Point: 10.1640

>T225076 WP_258611350.1 NZ_CP087189:180314-180595 [Pseudomonas protegens]
MTYSLEFLPSAHKEWNKLGHTLREQFKKKLAERLEVPRIPADALHGLPDCHKIKLKASCYRLVYQVIEERVVVCVVAVGK
RERGTVYEQARKR

Download         Length: 282 bp

>T225076 NZ_CP120946:c2556-1516 [Escherichia coli O157:H7 str. EDL933]
ATGGCACAGAACCCGTTTAAAGCACTAAATATCAATATTGACAAGATTGAGTCTGCTCTGACGCAGAATGGCGTCACAAA
CTATTCCTCTAATGTAAAAAACGAAAGAGAAACTCACATATCTGGCACATATAAAGGAATAGACTTCTTAATAAAACTAA
TGCCATCAGGCGGAAATACCACTATCGGAAGAGCGTCTGGGCAAAATAACACTTACTTTGATGAAATCGCCTTGATTATA
AAAGAAAACTGTTTGTATTCAGACACAAAGAACTTTGAATACACCATTCCAAAATTCAGTGATGATGACAGGGCAAATCT
ATTTGAATTTCTTTCTGAAGAGGGGATAACAATAACAGAAGATAATAATAACGATCCTAATTGTAAACACCAATATATTA
TGACCACCAGCAATGGTGACAGGGTCAGGGCAAAAATTTACAAGCGCGGCTCTATTCAATTCCAAGGAAAATACCTTCAA
ATCGCGAGTTTGATTAACGATTTCATGTGCTCAATACTAAACATGAAAGAGATTGTCGAACAAAAAAATAAAGAATTTAA
TGTTGACATAAAAAAAGAAACTATTGAGTCCGAGTTGCATAGCAAACTACCAAAAAGCATCGATAAAATCCATGAAGATA
TCAAAAAACAGCTATCATGCTCGCTAATAATGAAAAAAATAGATGTCGAAATGGAAGATTACTCAACATACTGCTTCTCT
GCATTAAGAGCCATAGAAGGCTTTATATATCAAATACTTAATGATGTTTGCAATCCATCATCATCAAAGAACCTTGGCGA
ATACTTCACTGAAAACAAACCCAAATATATAATCAGAGAAATACACCAAGAAACTATAAATGGTGAAATAGCGGAAGTTT
TGTGTGAATGCTACACTTACTGGCATGAGAACAGGCATGGTTTGTTTCATATGAAACCAGGAATAGCTGACACGAAGACA
ATTAACAAATTAGAATCAATCGCAATCATCGATACCGTTTGCCAATTAATAGATGGTGGCGTAGCTAGGTTGAAATTATG
A

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8799.10 Da        Isoelectric Point: 4.3988

>AT225076 WP_011058534.1 NZ_CP087189:180079-180324 [Pseudomonas protegens]
MQSILADKAVSVSELKKNPSAVLSGAQGGPVAVLNHNRVMGYMVPAEVFEALMERLDDLELAEIIRERSHETPVPVSLDD
L

Download         Length: 246 bp

>AT225076 NZ_CP120946:c1519-1139 [Escherichia coli O157:H7 str. EDL933]
ATGAAAAAAGATAAAAAATATCAAATAGAAGCAATAAAAAATAAAGATAAAACTTTATTTATTGTCTATGCTACTGATAT
TTATAGCCCGAGCGAATTTTTCTCAAAAATCGAATCCGACTTGAAGAAAAAGAAAAGCAAGGGTGATGTTTTTTTTGATT
TAATAATTCCTAACGGTGGAAAAAAAGATCGTTACGTCTATACGTCATTTAATGGCGAGAAGTTTTCAAGTTACACATTA
AACAAAGTTACGAAAACTGATGAATATAATGATTTATCTGAGCTCTCGGCTTCGTTCTTTAAAAAAAACTTTGATAAGAT
CAACGTAAACCTTCTATCCAAAGCCACATCATTTGCTTTGAAAAAAGGCATTCCAATATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB Q4KKD3

References