Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4674040..4674490 Replicon chromosome
Accession NZ_CP087188
Organism Pseudomonas laurylsulfatiphila strain B21-025

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY25_RS21025 Protein ID WP_258681992.1
Coordinates 4674040..4674309 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY25_RS21030 Protein ID WP_258681993.1
Coordinates 4674299..4674490 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY25_RS21000 (LOY25_20965) 4669903..4671516 + 1614 WP_258681987.1 sensor domain-containing diguanylate cyclase -
LOY25_RS21005 (LOY25_20970) 4671558..4671836 - 279 WP_258681988.1 hypothetical protein -
LOY25_RS21010 (LOY25_20975) 4671927..4672433 - 507 WP_258681989.1 PaaI family thioesterase -
LOY25_RS21015 (LOY25_20980) 4672500..4673036 - 537 WP_258681990.1 VOC family protein -
LOY25_RS21020 (LOY25_20985) 4673240..4673692 - 453 WP_258681991.1 hypothetical protein -
LOY25_RS21025 (LOY25_20990) 4674040..4674309 - 270 WP_258681992.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY25_RS21030 (LOY25_20995) 4674299..4674490 - 192 WP_258681993.1 antitoxin Antitoxin
LOY25_RS21035 (LOY25_21000) 4675054..4675401 + 348 WP_258681994.1 DUF6124 family protein -
LOY25_RS21040 (LOY25_21005) 4675425..4675517 - 93 Protein_4142 metal ABC transporter ATP-binding protein -
LOY25_RS21045 (LOY25_21010) 4675473..4675778 + 306 WP_258681995.1 hypothetical protein -
LOY25_RS21050 (LOY25_21015) 4675929..4676894 - 966 WP_258681996.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10457.99 Da        Isoelectric Point: 6.2181

>T225074 WP_258681992.1 NZ_CP087188:c4674309-4674040 [Pseudomonas laurylsulfatiphila]
MLVEWRPEARAELWQILNYIGDRNFVAASELFQAIEAATSSLPEHPYLYRFGRVLGTREIVVHPNYLVVYRVTDRIEILS
VLHARQEYP

Download         Length: 270 bp

>T225074 NZ_CP120945:c44434-44159 [Escherichia coli O157:H7 str. EDL933]
ATGGAACTGAAGTGGAGCAGTAAAGCGCTTTCTGATTTGGCGCGGTTATATGATTTTCTGGTGCTAGCCAGTAAACCTGC
TGCCGCCAGAACGGTACAGTCCCTGACACAGGCACCGGTCATTCTGTTAACTCATCCACGTATGGGGGAACAGTTATTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTGCTGGCGAGTACGAAATCCGTTACGAACTTAATGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7228.07 Da        Isoelectric Point: 5.0022

>AT225074 WP_258681993.1 NZ_CP087188:c4674490-4674299 [Pseudomonas laurylsulfatiphila]
MSTELSPIVSEFETKEQAASYDRWFRAKVQASLDDPRPNVPHDQVMADMRALIESKRNKYDAG

Download         Length: 192 bp

>AT225074 NZ_CP120945:c44718-44434 [Escherichia coli O157:H7 str. EDL933]
ATGCAAATGAAAAACAATACCGCACAAGCAACAAAAGTCATTACCGCGCATGTGCCATTACCTATGGCTGATAAAGTCGA
CCAGATGGCCGCCAGACTGGAACGCTCCCGGGGTTGGGTTATCAAACAGGCGCTTTCTGCATGGCTTGCCCAGGAGGAGG
AGCGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGGTTATTGACCATCAGGCTGTACAGGCCTGG
GCGGACAGCCTCAGTACTGACAATCCGTTACCGGTGCCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References