Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
| Location | 2166952..2167501 | Replicon | chromosome |
| Accession | NZ_CP087187 | ||
| Organism | Pseudomonas atacamensis strain B21-026 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LOY41_RS09560 | Protein ID | WP_122707090.1 |
| Coordinates | 2167226..2167501 (+) | Length | 92 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A554AG13 |
| Locus tag | LOY41_RS09555 | Protein ID | WP_041478584.1 |
| Coordinates | 2166952..2167224 (+) | Length | 91 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOY41_RS09535 (LOY41_09510) | 2162260..2162883 | + | 624 | WP_016774080.1 | isochorismate family cysteine hydrolase YcaC | - |
| LOY41_RS09540 (LOY41_09515) | 2163093..2164520 | - | 1428 | WP_073474277.1 | mechanosensitive ion channel family protein | - |
| LOY41_RS09545 (LOY41_09520) | 2164629..2165648 | - | 1020 | WP_258717478.1 | alpha/beta hydrolase | - |
| LOY41_RS09550 (LOY41_09525) | 2165884..2166783 | + | 900 | WP_024012435.1 | LysR family transcriptional regulator | - |
| LOY41_RS09555 (LOY41_09530) | 2166952..2167224 | + | 273 | WP_041478584.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
| LOY41_RS09560 (LOY41_09535) | 2167226..2167501 | + | 276 | WP_122707090.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LOY41_RS09565 (LOY41_09540) | 2167602..2168399 | + | 798 | WP_073474279.1 | class I SAM-dependent methyltransferase | - |
| LOY41_RS09570 (LOY41_09545) | 2168515..2168823 | - | 309 | WP_110646475.1 | putative addiction module antidote protein | - |
| LOY41_RS09575 (LOY41_09550) | 2169129..2169821 | - | 693 | WP_056784508.1 | hypothetical protein | - |
| LOY41_RS09580 (LOY41_09555) | 2169818..2171008 | - | 1191 | WP_122707092.1 | GNAT family N-acetyltransferase | - |
| LOY41_RS09585 (LOY41_09560) | 2171012..2171701 | - | 690 | WP_073474287.1 | N-acetyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10688.33 Da Isoelectric Point: 6.4700
>T225065 WP_122707090.1 NZ_CP087187:2167226-2167501 [Pseudomonas atacamensis]
MELKWTSKGLSDLTRLYEFLAAVNQPAAARTVQQLTAAPIMLLANPRLGESLEEFEPRDVRRILVGHYEMRYEIVDSTIY
LLRLWHTREER
MELKWTSKGLSDLTRLYEFLAAVNQPAAARTVQQLTAAPIMLLANPRLGESLEEFEPRDVRRILVGHYEMRYEIVDSTIY
LLRLWHTREER
Download Length: 276 bp
>T225065 NZ_CP120944:2947277-2947384 [Escherichia coli O157:H7 str. EDL933]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10092.46 Da Isoelectric Point: 5.6994
>AT225065 WP_041478584.1 NZ_CP087187:2166952-2167224 [Pseudomonas atacamensis]
MAAPMKTRSVTAHVPVQLAEKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQSVQAWADSL
SSDTPLKAPL
MAAPMKTRSVTAHVPVQLAEKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQSVQAWADSL
SSDTPLKAPL
Download Length: 273 bp
>AT225065 NZ_CP120944:c2947224-2947163 [Escherichia coli O157:H7 str. EDL933]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|