Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 175306..175822 Replicon chromosome
Accession NZ_CP087186
Organism Pseudomonas siliginis strain B21-063

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY48_RS00730 Protein ID WP_252877214.1
Coordinates 175541..175822 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2U1R4X8
Locus tag LOY48_RS00725 Protein ID WP_041477418.1
Coordinates 175306..175551 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY48_RS00705 (LOY48_00705) 170667..172205 + 1539 WP_258707424.1 MFS transporter -
LOY48_RS00710 (LOY48_00710) 172233..173300 + 1068 WP_150637840.1 HlyD family secretion protein -
LOY48_RS00715 (LOY48_00715) 173297..174892 + 1596 WP_258707425.1 efflux transporter outer membrane subunit -
LOY48_RS00720 (LOY48_00720) 174971..175216 + 246 WP_252885116.1 DUF2789 domain-containing protein -
LOY48_RS00725 (LOY48_00725) 175306..175551 + 246 WP_041477418.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LOY48_RS00730 (LOY48_00730) 175541..175822 + 282 WP_252877214.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY48_RS00735 (LOY48_00735) 176186..176614 + 429 WP_016772266.1 winged helix DNA-binding protein -
LOY48_RS00740 (LOY48_00740) 176611..178674 + 2064 WP_150742985.1 FUSC family protein -
LOY48_RS00745 (LOY48_00745) 178671..178880 + 210 WP_016772264.1 DUF1656 domain-containing protein -
LOY48_RS00750 (LOY48_00750) 178877..179764 + 888 WP_056786955.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10812.70 Da        Isoelectric Point: 10.5812

>T225052 WP_252877214.1 NZ_CP087186:175541-175822 [Pseudomonas siliginis]
MTYKLEFLPSAHKEWNKLGHTLREQFKKKLGERLKLPRIPADALHGMPDCYKIKLKASGYRLVYQVIDERVVVSVLAVGK
RERSSVYDAARNR

Download         Length: 282 bp

>T225052 NZ_CP120944:227730-227837 [Escherichia coli O157:H7 str. EDL933]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8806.13 Da        Isoelectric Point: 4.4988

>AT225052 WP_041477418.1 NZ_CP087186:175306-175551 [Pseudomonas siliginis]
MQSVLADMAVSVSELKKNPTAVLNGAHGGAVAVLNHNRVMGYMVPAEVYEAMMERLDDLELADIVRSRLHETPISVSLDD
L

Download         Length: 246 bp

>AT225052 NZ_CP120944:c227682-227616 [Escherichia coli O157:H7 str. EDL933]
GGTCTAGGTTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2U1R4X8

References