Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/upstrm_HI1419-dnstrm_HI1420 |
Location | 761677..762273 | Replicon | chromosome |
Accession | NZ_CP087182 | ||
Organism | Pseudomonas protegens strain B21-030 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A2C9EFT8 |
Locus tag | LOY23_RS03345 | Protein ID | WP_015633982.1 |
Coordinates | 761971..762273 (-) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q4KIY9 |
Locus tag | LOY23_RS03340 | Protein ID | WP_011059020.1 |
Coordinates | 761677..761967 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LOY23_RS03320 (LOY23_03320) | 757947..760079 | - | 2133 | WP_011059016.1 | TonB-dependent copper receptor | - |
LOY23_RS03325 (LOY23_03325) | 760168..760578 | - | 411 | WP_183000714.1 | DUF2946 domain-containing protein | - |
LOY23_RS03330 (LOY23_03330) | 760634..761128 | - | 495 | WP_065364905.1 | copper chaperone PCu(A)C | - |
LOY23_RS03335 (LOY23_03335) | 761178..761576 | - | 399 | WP_011059019.1 | DUF2946 domain-containing protein | - |
LOY23_RS03340 (LOY23_03340) | 761677..761967 | - | 291 | WP_011059020.1 | putative addiction module antidote protein | Antitoxin |
LOY23_RS03345 (LOY23_03345) | 761971..762273 | - | 303 | WP_015633982.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LOY23_RS03350 (LOY23_03350) | 762457..763185 | - | 729 | WP_072452000.1 | cobalt-precorrin-6A reductase | - |
LOY23_RS03355 (LOY23_03355) | 763182..764279 | - | 1098 | WP_077933276.1 | cobalt-precorrin-5B (C(1))-methyltransferase | - |
LOY23_RS03360 (LOY23_03360) | 764373..765587 | - | 1215 | WP_174395750.1 | precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE | - |
LOY23_RS03365 (LOY23_03365) | 765725..767038 | + | 1314 | WP_174395749.1 | precorrin-3B synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11504.34 Da Isoelectric Point: 10.6512
>T225029 WP_015633982.1 NZ_CP087182:c762273-761971 [Pseudomonas protegens]
MFVFEQTPEFSRWLLNLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVHEMRIHRGPGYRVYFSRRGKVIYLLLIGGDKA
TQKRDIQRARQLACDLKSEG
MFVFEQTPEFSRWLLNLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVHEMRIHRGPGYRVYFSRRGKVIYLLLIGGDKA
TQKRDIQRARQLACDLKSEG
Download Length: 303 bp
>T225029 NZ_CP120847:356620-356988 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10423.94 Da Isoelectric Point: 5.0939
>AT225029 WP_011059020.1 NZ_CP087182:c761967-761677 [Pseudomonas protegens]
MRTPVTRFDAAEYLKTPEDMVAYLDACFEEDTGDGVLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKINVSNA
MRTPVTRFDAAEYLKTPEDMVAYLDACFEEDTGDGVLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKINVSNA
Download Length: 291 bp
>AT225029 NZ_CP120847:356402-356623 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2C9EFT8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q4KIY9 |