Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | slvAT/RES(toxin) |
Location | 811572..812302 | Replicon | chromosome |
Accession | NZ_CP087181 | ||
Organism | Pseudomonas sp. B21-031 |
Toxin (Protein)
Gene name | slvT | Uniprot ID | - |
Locus tag | LOY53_RS03715 | Protein ID | WP_252826665.1 |
Coordinates | 811572..811910 (-) | Length | 113 a.a. |
Antitoxin (Protein)
Gene name | slvA | Uniprot ID | - |
Locus tag | LOY53_RS03720 | Protein ID | WP_252826666.1 |
Coordinates | 811907..812302 (-) | Length | 132 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LOY53_RS03695 (LOY53_03695) | 806605..807822 | - | 1218 | WP_252826661.1 | DUF3422 domain-containing protein | - |
LOY53_RS03700 (LOY53_03700) | 807990..809420 | - | 1431 | WP_252826662.1 | aldehyde dehydrogenase family protein | - |
LOY53_RS03705 (LOY53_03705) | 809434..810933 | - | 1500 | WP_252826663.1 | cytosine permease | - |
LOY53_RS03710 (LOY53_03710) | 811027..811416 | - | 390 | WP_252826664.1 | nuclear transport factor 2 family protein | - |
LOY53_RS03715 (LOY53_03715) | 811572..811910 | - | 339 | WP_252826665.1 | RES family NAD+ phosphorylase | Toxin |
LOY53_RS03720 (LOY53_03720) | 811907..812302 | - | 396 | WP_252826666.1 | DUF2384 domain-containing protein | Antitoxin |
LOY53_RS03725 (LOY53_03725) | 812462..813481 | + | 1020 | WP_258703616.1 | transporter | - |
LOY53_RS03730 (LOY53_03730) | 813572..814192 | + | 621 | WP_027594492.1 | isochorismate family cysteine hydrolase YcaC | - |
LOY53_RS03735 (LOY53_03735) | 814431..815249 | + | 819 | WP_252826667.1 | polyphosphate kinase 2 | - |
LOY53_RS03740 (LOY53_03740) | 815286..816482 | + | 1197 | WP_252826668.1 | monovalent cation:proton antiporter-2 (CPA2) family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 113 a.a. Molecular weight: 12146.92 Da Isoelectric Point: 9.4424
>T225025 WP_252826665.1 NZ_CP087181:c811910-811572 [Pseudomonas sp. B21-031]
MKIIAYRNLACYRLHTPKWAIAPMSGAGAATQGGRANRKGLEALYLSLEPATAVAEFQQGSPFLPPGLLVSYSLTLDLVL
YTDQLPAHGSITVNDPRGDLPKDQSSWHRPKS
MKIIAYRNLACYRLHTPKWAIAPMSGAGAATQGGRANRKGLEALYLSLEPATAVAEFQQGSPFLPPGLLVSYSLTLDLVL
YTDQLPAHGSITVNDPRGDLPKDQSSWHRPKS
Download Length: 339 bp
>T225025 NZ_CP120837:4490189-4490500 [Salmonella enterica subsp. enterica]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACACTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGCACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATATGATCGGGGTAATAAAGAATGA
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACACTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGCACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATATGATCGGGGTAATAAAGAATGA
Antitoxin
Download Length: 132 a.a. Molecular weight: 14986.05 Da Isoelectric Point: 5.6928
>AT225025 WP_252826666.1 NZ_CP087181:c812302-811907 [Pseudomonas sp. B21-031]
MASNAVLELHPTTFEGLMEALREVNRVMFSPERFLKVFSMDQQTFAARAHVHRNTVRNAPESEKIQAYIRDAVRVLRALT
DMGTEMTKAIFWFKNEPLSTFDYKTAEEVVSEGRTEQLIAFLQSWEAGAQG
MASNAVLELHPTTFEGLMEALREVNRVMFSPERFLKVFSMDQQTFAARAHVHRNTVRNAPESEKIQAYIRDAVRVLRALT
DMGTEMTKAIFWFKNEPLSTFDYKTAEEVVSEGRTEQLIAFLQSWEAGAQG
Download Length: 396 bp
>AT225025 NZ_CP120837:4490497-4490943 [Salmonella enterica subsp. enterica]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAAGCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAAGCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|