Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
| Location | 1492470..1494163 | Replicon | chromosome |
| Accession | NZ_CP087180 | ||
| Organism | Pseudomonas sp. B21-032 | ||
Toxin (Protein)
| Gene name | doc | Uniprot ID | - |
| Locus tag | LOY54_RS06880 | Protein ID | WP_258609993.1 |
| Coordinates | 1493294..1494163 (-) | Length | 290 a.a. |
Antitoxin (Protein)
| Gene name | phd | Uniprot ID | A0A1H1EW67 |
| Locus tag | LOY54_RS06875 | Protein ID | WP_045193445.1 |
| Coordinates | 1492470..1493297 (-) | Length | 276 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOY54_RS06855 (LOY54_06855) | 1487678..1489168 | - | 1491 | WP_195885900.1 | aldehyde dehydrogenase | - |
| LOY54_RS06860 (LOY54_06860) | 1489179..1489982 | - | 804 | WP_045193450.1 | aspartate dehydrogenase | - |
| LOY54_RS06865 (LOY54_06865) | 1489993..1491675 | - | 1683 | WP_258609988.1 | thiamine pyrophosphate-binding protein | - |
| LOY54_RS06870 (LOY54_06870) | 1491668..1492468 | - | 801 | WP_258609990.1 | SDR family oxidoreductase | - |
| LOY54_RS06875 (LOY54_06875) | 1492470..1493297 | - | 828 | WP_045193445.1 | IclR family transcriptional regulator | Antitoxin |
| LOY54_RS06880 (LOY54_06880) | 1493294..1494163 | - | 870 | WP_258609993.1 | alpha/beta hydrolase | Toxin |
| LOY54_RS06885 (LOY54_06885) | 1494168..1494707 | - | 540 | WP_093386119.1 | cupin domain-containing protein | - |
| LOY54_RS06890 (LOY54_06890) | 1494722..1495486 | - | 765 | WP_258609995.1 | SDR family oxidoreductase | - |
| LOY54_RS06895 (LOY54_06895) | 1495486..1496262 | - | 777 | WP_045193442.1 | ABC transporter permease | - |
| LOY54_RS06900 (LOY54_06900) | 1496292..1497290 | - | 999 | WP_258609997.1 | ABC transporter substrate-binding protein | - |
| LOY54_RS06905 (LOY54_06905) | 1497330..1498166 | - | 837 | WP_045193440.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 290 a.a. Molecular weight: 30654.93 Da Isoelectric Point: 6.9551
>T225023 WP_258609993.1 NZ_CP087180:c1494163-1493294 [Pseudomonas sp. B21-032]
MLHATDHSLAGLAAQLQQRFPQRLVQLASGAQAIREAGHGPAIVLLHGIGSGAASWLQVALQLSQQARVIAWDAPGYGDS
SPLANPAPQAADYARRLRQLLDALQIDDCLLVGHSLGALSAAALTQQQPQRVRRLVLISPARGYGDPARAEQAQQVRSQR
LHNLEQLGIAQMANQRSAHMLSPAASSEARAWVQWNMARLLPQGYRQAIELLCGDDLLRYAALAVPCEVHCGAADSITRP
EDCQALAKALGAAFALIAEAGHASPIEQPEAVASLLARALEESLTGTAL
MLHATDHSLAGLAAQLQQRFPQRLVQLASGAQAIREAGHGPAIVLLHGIGSGAASWLQVALQLSQQARVIAWDAPGYGDS
SPLANPAPQAADYARRLRQLLDALQIDDCLLVGHSLGALSAAALTQQQPQRVRRLVLISPARGYGDPARAEQAQQVRSQR
LHNLEQLGIAQMANQRSAHMLSPAASSEARAWVQWNMARLLPQGYRQAIELLCGDDLLRYAALAVPCEVHCGAADSITRP
EDCQALAKALGAAFALIAEAGHASPIEQPEAVASLLARALEESLTGTAL
Download Length: 870 bp
>T225023 NZ_CP120837:c4179719-4179228 [Salmonella enterica subsp. enterica]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA
Antitoxin
Download Length: 276 a.a. Molecular weight: 30416.81 Da Isoelectric Point: 6.3865
>AT225023 WP_045193445.1 NZ_CP087180:c1493297-1492470 [Pseudomonas sp. B21-032]
MNDSDLLKDNQDKYIVPGLERGLLLLCEFSRQNRTLTAPELARRLELPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDHLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVLELFDLVQSDRQRGYVSGEGFFESSISTIAAPVRDHSGRVVAAMGVTIPTVQVAHINF
DGLLGHVRGSADELSRLLNYTPNAGSGRVTALMRD
MNDSDLLKDNQDKYIVPGLERGLLLLCEFSRQNRTLTAPELARRLELPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDHLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVLELFDLVQSDRQRGYVSGEGFFESSISTIAAPVRDHSGRVVAAMGVTIPTVQVAHINF
DGLLGHVRGSADELSRLLNYTPNAGSGRVTALMRD
Download Length: 828 bp
>AT225023 NZ_CP120837:c4180009-4179716 [Salmonella enterica subsp. enterica]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATTGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGTGCTGCCGCCGAGGAAGCGCTGA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATTGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGTGCTGCCGCCGAGGAAGCGCTGA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|