Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2735775..2736294 Replicon chromosome
Accession NZ_CP087177
Organism Pseudomonas moraviensis strain B21-039

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY57_RS11830 Protein ID WP_258641301.1
Coordinates 2736010..2736294 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY57_RS11825 Protein ID WP_258641458.1
Coordinates 2735775..2736023 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY57_RS11805 (LOY57_11775) 2731331..2732341 + 1011 WP_064361775.1 AAA family ATPase -
LOY57_RS11810 (LOY57_11780) 2732257..2733006 + 750 WP_258641298.1 VWA domain-containing protein -
LOY57_RS11815 (LOY57_11785) 2733398..2734957 + 1560 WP_064361773.1 TerC family protein -
LOY57_RS11820 (LOY57_11790) 2735095..2735526 - 432 WP_258641300.1 thioredoxin family protein -
LOY57_RS11825 (LOY57_11795) 2735775..2736023 + 249 WP_258641458.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LOY57_RS11830 (LOY57_11800) 2736010..2736294 + 285 WP_258641301.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY57_RS11835 (LOY57_11805) 2736575..2737423 + 849 WP_258641302.1 transporter substrate-binding domain-containing protein -
LOY57_RS11840 (LOY57_11810) 2737475..2738137 + 663 WP_258641303.1 amino acid ABC transporter permease -
LOY57_RS11845 (LOY57_11815) 2738147..2738809 + 663 WP_065617203.1 amino acid ABC transporter permease -
LOY57_RS11850 (LOY57_11820) 2738806..2739597 + 792 WP_065617204.1 amino acid ABC transporter ATP-binding protein -
LOY57_RS11855 (LOY57_11825) 2739629..2740018 + 390 WP_042610358.1 RidA family protein -
LOY57_RS11860 (LOY57_11830) 2740148..2740912 + 765 WP_065617205.1 IclR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10932.78 Da        Isoelectric Point: 11.0123

>T225014 WP_258641301.1 NZ_CP087177:2736010-2736294 [Pseudomonas moraviensis]
MRTYELEFSDKAWREWGKLGSELRQQFKNKLLERLANPHVPAARLKGLSNAYKIKLRSAGYRLVYRVRDEVLVVTVIAVG
KRQGGDVYKQALKR

Download         Length: 285 bp

>T225014 NZ_CP120837:836168-836566 [Salmonella enterica subsp. enterica]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTCTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAACTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCGGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAATTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9071.49 Da        Isoelectric Point: 4.7905

>AT225014 WP_258641458.1 NZ_CP087177:2735775-2736023 [Pseudomonas moraviensis]
MTHIVLSHVVASISELKKNPMGTVAAGGGRSVAILNRNEPAFYCVPAKEYEAMMERLDDLELIALCRERENDPTIKVSIE
DL

Download         Length: 249 bp

>AT225014 NZ_CP120837:835941-836168 [Salmonella enterica subsp. enterica]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGTAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References