Detailed information of TA system TA225003

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 2751644..2752106
• Replicon: chromosome
• Accession: NZ_CP087175
• Organism: Pseudomonas sp. B21-041

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LOY43_RS12240
• Protein ID: WP_256579944.1
• Coordinates: 2751644..2751865 (-)
• Length: 74 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LOY43_RS12245
• Protein ID: WP_258709727.1
• Coordinates: 2751912..2752106 (-)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LOY43_RS12240 (LOY43_12210)	2751644..2751865	-	222	WP_256579944.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LOY43_RS12245 (LOY43_12215)	2751912..2752106	-	195	WP_258709727.1	stability determinant	Antitoxin
LOY43_RS12250 (LOY43_12220)	2752361..2753308	-	948	WP_258709728.1	transporter	-
LOY43_RS12255 (LOY43_12225)	2753520..2754617	+	1098	WP_258709729.1	AraC family transcriptional regulator	-
LOY43_RS12260 (LOY43_12230)	2754934..2755821	+	888	WP_095126454.1	Dyp-type peroxidase	-
LOY43_RS12265 (LOY43_12235)	2755832..2756800	+	969	WP_258709730.1	Gfo/Idh/MocA family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-69)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 74 a.a.
• Molecular weight: 8279.48 Da
• Isoelectric Point: 11.4092

>T225003 WP_256579944.1 NZ_CP087175:c2751865-2751644 [Pseudomonas sp. B21-041]
IEQYNSNASAALQRKVGAATQRLSSIPYGYRSGRVPGTREMVVNPNYLLVYRVNGRIKILTLVHTRQQYPRTS

Nucleotide

• Length: 222 bp

>T225003 NZ_CP120732:c804226-803906 [Burkholderia vietnamiensis]
ATGGTGATGCGCGGGGAAGTCTGGTTGGTCGCACTCGATCCGACGCTTGGTAGCGAGATTCAAAAGACGCGCCCCTGTGT
GGTCGTTTCACCTCCCGAAATGCACGACCACTTGCGCACTGTCATCGTCGCGCCGATGACTTCCAAGGGGCGTCCAGTGC
CGTTTCGGATTCCGGTTACGTTCAAGCGCAAACATGGTTTGATCCTTCTGGATCAGATTCGCGCAGTGGACAAGGTGCGC
TTGGTTAAGAAAGAGGGTGCAGTTGCCGATAAAACGTTGTTGGATACCCTGCGGACCTTGCAGGAAGTCTTTGCGGAATA
A

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7535.41 Da
• Isoelectric Point: 4.6234

>AT225003 WP_258709727.1 NZ_CP087175:c2752106-2751912 [Pseudomonas sp. B21-041]
MSILLSPFYSEFESEEEAESYDRWFRAKVQAALDDPRPGIPHEEAMVRLDQLLEEKRKNRHTAA

Nucleotide

• Length: 195 bp

>AT225003 NZ_CP120732:c804468-804220 [Burkholderia vietnamiensis]
ATGAAGACGACGATTCGCAGAATGGGCAACTCGCAGGGCGTGCTGATTCCGAAGCCCGTCCTTGCGCAACTCGGGCTGGA
GAGCGAAGTGGAAATGGAGGTCGAGAACGACGCGATTGTTCTGCGCCGCCCGAAGCACAAAGCCCGTGAGGGGTGGGCGG
AAGCAAGCAAGGCTCTGGCCGAGAGCGGCGACGATGCGCTGGTTATGGGCGAGTTTTCGAACGCCGATGACGCGGAGCTT
GCATGGTGA