225002

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2343077..2343557 Replicon chromosome
Accession NZ_CP087175
Organism Pseudomonas sp. B21-041

Toxin (Protein)


Gene name relE Uniprot ID A0A7H8GNS0
Locus tag LOY43_RS10380 Protein ID WP_016983362.1
Coordinates 2343077..2343361 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4V6Q6W5
Locus tag LOY43_RS10385 Protein ID WP_034152589.1
Coordinates 2343351..2343557 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY43_RS10345 (LOY43_10315) 2338488..2338961 + 474 WP_102902833.1 type II secretion system protein -
LOY43_RS10350 (LOY43_10320) 2338967..2339341 + 375 WP_007919395.1 type II secretion system protein -
LOY43_RS10355 (LOY43_10325) 2339316..2339855 + 540 WP_123374842.1 type II secretion system protein -
LOY43_RS10360 (LOY43_10330) 2339852..2340244 + 393 WP_258709561.1 curli production assembly/transport protein CsgE -
LOY43_RS10365 (LOY43_10335) 2340241..2340672 + 432 WP_016987875.1 curli assembly protein CsgF -
LOY43_RS10370 (LOY43_10340) 2340702..2341562 + 861 WP_258709562.1 CsgG/HfaB family protein -
LOY43_RS10375 (LOY43_10345) 2342524..2342895 + 372 WP_095047565.1 DUF6124 family protein -
LOY43_RS10380 (LOY43_10350) 2343077..2343361 - 285 WP_016983362.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY43_RS10385 (LOY43_10355) 2343351..2343557 - 207 WP_034152589.1 hypothetical protein Antitoxin
LOY43_RS10390 (LOY43_10360) 2343834..2345285 - 1452 WP_258709563.1 curlin -
LOY43_RS10395 (LOY43_10365) 2345313..2345777 - 465 WP_110721043.1 curlin -
LOY43_RS10400 (LOY43_10370) 2345851..2348079 - 2229 WP_258709564.1 Ig-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10866.69 Da        Isoelectric Point: 10.6629

>T225002 WP_016983362.1 NZ_CP087175:c2343361-2343077 [Pseudomonas sp. B21-041]
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALCWHPHLYRKGRSPGTREIVVSPNYLVVYQVADQIEIVS
ILHARQEYPRRDPG

Download         Length: 285 bp

>T225002 NZ_CP120732:c293830-293396 [Burkholderia vietnamiensis]
GTGATTACCTACCTTCTCGACGTCAACGTACTCATTGCTTTGCTCGACCCGGCACACGTTCAACACGAGCCGGCGCATGC
GTGGTTTGGCCGGGTAGGCCATTCCGCATGGGCCACGTGCCCGCTCACCGAGAACGGCGTGCTTCGAATTATCGGCAATC
CGAAATACCCGAATACGATGGTCTCTCCTGCATCCGTTGCACCGCTTGTTGTGCAACTGCGGTCCCATGCTGGGCACACA
TTCTGGTCGGACGATGTGAGCCTGCTCGACGAAAAACACGTCGACGCCACCCGTTTACTGTCCTCCGCTCAACTGACCGA
CACTTACCTCCTCGCGCTCGCTCGCGCACACAAAGGCAAGTTGGCGACCTTCGATCGCCGCTTGGTCGTCGACGCGGTTC
CGAACGGCGGGAAGCATCTTGAACTGATTCCTTGA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7672.54 Da        Isoelectric Point: 3.8068

>AT225002 WP_034152589.1 NZ_CP087175:c2343557-2343351 [Pseudomonas sp. B21-041]
MIDPSLIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMEEINALMESMRKSADAD

Download         Length: 207 bp

>AT225002 NZ_CP120732:c294081-293827 [Burkholderia vietnamiensis]
ATGTCTGATGCTTACAAGGAGCGCAATATGCGTACCACTATTGATATCGACGACGACGTCCTTGCCTTCGCGCGGGAGCG
TGCAAAGCCCGGCACGAGTATCGGGAAGGTCATTTCTGACCTCGCCCGTGCGGCCCTGCAGCGCGGAACAACGAACCAGT
CGAGCCGAAACGGCTTGCCGTTGATGCCGGTTTCCGCGACCGCCCGTCCGGTCACCCTTGATACCGTTAATCAACTTCGC
GACGACTCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7H8GNS0

Antitoxin

Source ID Structure
AlphaFold DB A0A4V6Q6W5

References