Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 709205..709801 Replicon chromosome
Accession NZ_CP087175
Organism Pseudomonas sp. B21-041

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY43_RS03020 Protein ID WP_122606498.1
Coordinates 709499..709801 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY43_RS03015 Protein ID WP_077570750.1
Coordinates 709205..709495 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY43_RS02995 (LOY43_02990) 705496..707616 - 2121 WP_258709172.1 TonB-dependent copper receptor -
LOY43_RS03000 (LOY43_02995) 707701..708159 - 459 WP_258709173.1 DUF2946 domain-containing protein -
LOY43_RS03005 (LOY43_03000) 708181..708660 - 480 WP_258709174.1 copper chaperone PCu(A)C -
LOY43_RS03010 (LOY43_03005) 708709..709107 - 399 WP_122599673.1 DUF2946 domain-containing protein -
LOY43_RS03015 (LOY43_03010) 709205..709495 - 291 WP_077570750.1 putative addiction module antidote protein Antitoxin
LOY43_RS03020 (LOY43_03015) 709499..709801 - 303 WP_122606498.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY43_RS03025 (LOY43_03020) 709973..710689 - 717 WP_258709175.1 cobalt-precorrin-6A reductase -
LOY43_RS03030 (LOY43_03025) 710686..711783 - 1098 WP_258709176.1 cobalt-precorrin-5B (C(1))-methyltransferase -
LOY43_RS03035 (LOY43_03030) 711776..712987 - 1212 WP_095126116.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
LOY43_RS03040 (LOY43_03035) 713030..714415 + 1386 WP_095126115.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(7-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11495.20 Da        Isoelectric Point: 9.7106

>T224999 WP_122606498.1 NZ_CP087175:c709801-709499 [Pseudomonas sp. B21-041]
MIAFERSRIFSEWLDSLKDIKGKGRIISRIKTAENGNFGDCGFVGDTVYEMRVHYGPGYRMYFTRKGEVIYLLLIGGDKS
TQKRDIKRAVQMAHNIGNEE

Download         Length: 303 bp

>T224999 NZ_CP120730:1283983-1284384 [Burkholderia vietnamiensis]
ATGCCGCGCTATATGCTCGACACCAACATGTGCATCTACTTGATGAAGAGCCAGCCCGAGCAAGTGGCGAAGCGATTTGC
GCAGTGCTACACGGGCGACGTCGTGATGTCGGCGATCACATATGCCGAGCTGGAGTACGGCGTTACCGCTTGCGCGGCGC
CCGCGCGTGAGCGCCGCCATCTTGCGGCGCTGATCGAGGATATTCCCGTCGCGCCGTTCGACGCCGCGGCCGCGCAAGCA
TATGGGCCGGTGCGTGACGCAACGCGCGCATGGAAGAAGGATCATCTCGACAAACTGATCGCCGCTCATGCGGTGTCGCT
CGATGTCGTGCTGGTGACGAATGACGAGCGCGATTTCACGAGCTATCCGGGATTGCGGCTGGAGAACTGGCTGAACGATT
AG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10431.85 Da        Isoelectric Point: 4.3525

>AT224999 WP_077570750.1 NZ_CP087175:c709495-709205 [Pseudomonas sp. B21-041]
MSEEFARFDAAEYLKTPEDMAAYLDACFDDDEGDGVLIRAALNDIARAQGMTQVARDAGLGRESLYKALSSTGNPEFATI
MKVMKALGLRLHAVTL

Download         Length: 291 bp

>AT224999 NZ_CP120730:1283747-1283983 [Burkholderia vietnamiensis]
ATGCATACCACGAGGGTATTTCGGAACGGCAATTCGCAGGCCGTGCGAATTCCTGCGGATCTCGCTTATGAGCGCAGCGA
TATCGAGCTCGAGATCGAGCGCATCGGCGACGAGATCCGCATCCGGCCGGCGCGACGGCCGTTGACGCAGGTGCTCAAGA
AGTTCGCGAAGTTCGCGCCCGATTTCATGGCGGAAGGGCGTGGCGACCACGAGCAGGCCGAACGCGAGGGGTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References