Detailed information of TA system TA224992

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3350575..3351028
• Replicon: chromosome
• Accession: NZ_CP087171
• Organism: Pseudomonas atacamensis strain B21-045

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LOY27_RS14890
• Protein ID: WP_240995584.1
• Coordinates: 3350807..3351028 (+)
• Length: 74 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LOY27_RS14885
• Protein ID: WP_110645437.1
• Coordinates: 3350575..3350769 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LOY27_RS14860 (LOY27_14825)	3345778..3346575	+	798	WP_258710062.1	ATP-binding cassette domain-containing protein	-
LOY27_RS14865 (LOY27_14830)	3346569..3347396	+	828	WP_024013147.1	ABC transporter permease	-
LOY27_RS14870 (LOY27_14835)	3347393..3348160	+	768	WP_024013148.1	phosphonate ABC transporter, permease protein PhnE	-
LOY27_RS14875 (LOY27_14840)	3348339..3350018	+	1680	WP_122698146.1	MFS transporter	-
LOY27_RS14880 (LOY27_14845)	3350126..3350344	+	219	WP_024013150.1	hypothetical protein	-
LOY27_RS14885 (LOY27_14850)	3350575..3350769	+	195	WP_110645437.1	stability determinant	Antitoxin
LOY27_RS14890 (LOY27_14855)	3350807..3351028	+	222	WP_240995584.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-72)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 74 a.a.
• Molecular weight: 8440.86 Da
• Isoelectric Point: 11.2155

>T224992 WP_240995584.1 NZ_CP087171:3350807-3351028 [Pseudomonas atacamensis]
IDYVEQRNTVASVALHQKISAAARRLSWIPHGFRSGRIPGTREMVINSNYLLVYRVTDHIKILTLLHARKKYP

Nucleotide

• Length: 222 bp

>T224992 NZ_CP120711:c3883699-3882953 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATTATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCCGAATCACTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAAAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7330.25 Da
• Isoelectric Point: 4.3085

>AT224992 WP_110645437.1 NZ_CP087171:3350575-3350769 [Pseudomonas atacamensis]
MSAELSLIVSDFETEEEAAEYDLWYRAKVQAALDDPRPPIPHDEAMVLLGQMLEERRKNRRAAG

Nucleotide

• Length: 195 bp

>AT224992 NZ_CP120711:c3882952-3882782 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA