224979

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 600983..602679 Replicon chromosome
Accession NZ_CP087169
Organism Pseudomonas sp. B21-047

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LOY26_RS02750 Protein ID WP_258714888.1
Coordinates 602068..602679 (-) Length 204 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LOY26_RS02745 Protein ID WP_258714367.1
Coordinates 600983..602071 (-) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY26_RS02730 (LOY26_02730) 596314..597258 - 945 WP_258714365.1 FecR domain-containing protein -
LOY26_RS02735 (LOY26_02735) 597251..597790 - 540 WP_033703427.1 sigma-70 family RNA polymerase sigma factor -
LOY26_RS02740 (LOY26_02740) 597979..600918 + 2940 WP_258714366.1 TonB-dependent receptor -
LOY26_RS02745 (LOY26_02745) 600983..602071 - 1089 WP_258714367.1 macro domain-containing protein Antitoxin
LOY26_RS02750 (LOY26_02750) 602068..602679 - 612 WP_258714888.1 DUF4433 domain-containing protein Toxin
LOY26_RS02755 (LOY26_02755) 602693..603142 - 450 WP_258714368.1 DUF4433 domain-containing protein -
LOY26_RS02760 (LOY26_02760) 603627..604328 - 702 WP_258714369.1 XRE family transcriptional regulator -
LOY26_RS02765 (LOY26_02765) 604507..605034 - 528 WP_016497835.1 inorganic diphosphatase -
LOY26_RS02770 (LOY26_02770) 605127..605942 - 816 WP_186660645.1 zinc-dependent peptidase -
LOY26_RS02775 (LOY26_02775) 605951..606598 - 648 WP_033703417.1 DedA family protein -
LOY26_RS02780 (LOY26_02780) 606788..607246 - 459 WP_186660647.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-202)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 204 a.a.        Molecular weight: 23676.14 Da        Isoelectric Point: 7.5711

>T224979 WP_258714888.1 NZ_CP087169:c602679-602068 [Pseudomonas sp. B21-047]
MIWRIVHRDNLPWILDNGLHCANSDVRAPQYVNIGNAELIDKRRSRHVPIAPKGVLADYVPFYFTPFSVMMKNIHSGWSV
QQFSNDEIVILVSSLYRVEELGLPFVFTNAHAYPEWTNYYSDLAYLGEIDWPILQRRDFKRDPDDPRKMERYQAEALIHH
HLPITGLLGIMCYTDAVKKRIEHNVAARGLTLSVHARPGWYFQ

Download         Length: 612 bp

>T224979 NZ_CP120681:c714077-713331 [Bacillus subtilis]
ATGGTTTTATTCTTTCAGATCATGGTCTGGTGCATCGTGGCCGGACTGGGGTTATACGTGTATGCCACGTGGCGTTTCGA
AGCGAAGGTCAAAGAAAAAATGTCCGCCATTCGGAAAACTTGGTATTTGCTGTTTGTTCTGGGCGCTATGGTATACTGGA
CATATGAGCCCACTTCCCTATTTACCCACTGGGAACGGTATCTCATTGTCGCAGTCAGTTTTGCTTTGATTGATGCTTTT
ATCTTCTTAAGTGCATATGTCAAAAAACTGGCCGGCAGCGAGCTTGAAACAGACACAAGAGAAATTCTTGAAGAAAACAA
CGAAATGCTCCACATGTATCTCAATCGGCTGAAAACATACCAATACCTATTGAAAAACGAACCGATCCATGTTTATTATG
GAAGTATAGATGCTTATGCTGAAGGTATTGATAAGCTGCTGAAAACCTATGCTGATAAAATGAACTTAACGGCTTCTCTT
TGCCACTATTCGACACAGGCTGATAAAGACCGGTTAACCGAGCATATGGATGATCCGGCAGATGTACAAACACGGCTCGA
TCGAAAGGATGTTTATTACGACCAATACGGAAAAGTGGTTCTCATCCCTTTTACCATCGAGACACAGAACTATGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTATTTACGTCATTAACGAGCATATATGATTTGGTGCTG
CCAATTGAGGAGGAAGGTGAAGGATAA

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40703.81 Da        Isoelectric Point: 6.6150

>AT224979 WP_258714367.1 NZ_CP087169:c602071-600983 [Pseudomonas sp. B21-047]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAENYRLYAAACKAGEVVTGKVHVTAVNELDGPRWIINFPTK
RHWRSPSQMDWVTDGLYDLRHFLIENRVMSVAVPPLGAGNGGLKWPDVREQIIAVLGDLDVDVLVYEPVSQYLNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERTIEKLPNTENPLNLKFVAHRYGPYANRLQHLLNDLDGSYLH
CEKRINDAGIGDVIWFDETRKTFLQTYLKTEAKAYSQALERTVELIDGFESPFGMELLATVDWLLSEQGVSPTVPDVRES
LRHWEGGAGAAARKSKLFDDQALDIALKRLTSSGIKPEMASS

Download         Length: 1089 bp

>AT224979 NZ_CP120681:c713331-713161 [Bacillus subtilis]
ATGGAACGTGCGTTTCAAAACAGATGCGAGCCCAGAGCGGCGAAGCCGTTTAAAATCCTGAAAAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGTCCGCATACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References