Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 304796..305401 Replicon chromosome
Accession NZ_CP087169
Organism Pseudomonas sp. B21-047

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LOY26_RS01330 Protein ID WP_186661448.1
Coordinates 304796..305086 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY26_RS01335 Protein ID WP_186661410.1
Coordinates 305096..305401 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY26_RS01310 (LOY26_01310) 301082..302467 + 1386 WP_033703189.1 GABA permease -
LOY26_RS01315 (LOY26_01315) 302543..302980 - 438 WP_033703188.1 hypothetical protein -
LOY26_RS01320 (LOY26_01320) 303110..303643 + 534 WP_050506183.1 hypothetical protein -
LOY26_RS01325 (LOY26_01325) 303653..304633 - 981 WP_258714316.1 polyphosphate kinase 2 -
LOY26_RS01330 (LOY26_01330) 304796..305086 + 291 WP_186661448.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY26_RS01335 (LOY26_01335) 305096..305401 + 306 WP_186661410.1 putative addiction module antidote protein Antitoxin
LOY26_RS01345 (LOY26_01345) 305709..305981 - 273 WP_033703186.1 oxidative damage protection protein -
LOY26_RS01350 (LOY26_01350) 305978..307045 - 1068 WP_033703185.1 A/G-specific adenine glycosylase -
LOY26_RS01355 (LOY26_01355) 307042..309291 - 2250 WP_033703184.1 AsmA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10934.64 Da        Isoelectric Point: 10.2803

>T224978 WP_186661448.1 NZ_CP087169:304796-305086 [Pseudomonas sp. B21-047]
MHTLIQTDRYRRWFSALRDDRAQARINIRLRRIELGVLGDCKPVGEGVSELRIDYGPGYRVYFVQRGYEVIILLAGGDKA
SQAADIKSALKLARNL

Download         Length: 291 bp

>T224978 NZ_CP120679:c1442738-1441992 [Bacillus sp. HSf4]
ATGCTGCTATTTTATCAATTCCTTGTTTGGCTCATTGTTTTGGCGCTGGCTCTGTACGTGGCTGCCGTGTGGCGTTTTGA
AAAAAAGCTCACCGAAAAAACGGTCGCGATCAGAAAAACGTGGTACCTGCTTTATGTTATCGGCGCCGTGATTTATTGGA
CGCACGATCCGCAGTCGATTTTCACGAATCCGCTTCATTACCTGATCGTCGCCGTTTTCTTCACGCTCACCGATGCTTTT
ATTTTTTTAAACGCCTATTTTAAAAAACTCGGAAGTTCTGAACTCGCCACAGACACAAGGATGCTTCTCGAAGAAAACAA
CGACCTGCTTCACACTTATCAAAACAGGCTGAAAACGTACCAATACCTATTGAAAAACGAACCGATCCACATCTATTATG
GAAGTATAGAAGCTTATGCTGAAGGCATTGAAAAACTCATCAGCCGCTTTGGCGAAAAAATGAATATTTCTGCCGCCTTA
TGTGAATATAATTCAAACGAGAGCAAGGATCATTTGCTTGAACACATGGAAAACCGGTTCGCCGTTCAAGAAAAGCTGGA
TCGGAAAGACGTCTATTACGAAGAAAACGGAAAAATGGTCCTGATTCCATTTTCGATCCATGATTATGACTATGTGATGA
AATTAACCTCAGAGGATCTGGTCACAGAATTCGACTACCTCCTGTTTACTTCTTTAACAAGCGTCTATGATCTCCTGCTA
CCAAACGAAGAGGAAGGTGACGATTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10805.56 Da        Isoelectric Point: 5.1006

>AT224978 WP_186661410.1 NZ_CP087169:305096-305401 [Pseudomonas sp. B21-047]
MTDIKLSKWDVVDHLKSEKDMVLYLEACLEENDPALLAAALGDIARARGMAQLARDTGLTREGLYKALSAEGNPSLATIM
KVMAALGVRLHAEVVPAQVSG

Download         Length: 306 bp

>AT224978 NZ_CP120679:c1441990-1441826 [Bacillus sp. HSf4]
ATGGAGCCTGCTTTTCAGGAAAACGCAAAGAAGCGCCTTTCATTTAAAATGTTTAAAAAGCAATCGAAAACCAGTATCGC
AAAATACGAAGTCAGCCCCCACACCGAACGGATTTTCAAACAAAACGAACGGCTGATAGGCGAGTATAAACGGAAAAAAG
CCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References