224977

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-higA/HigB-HigA
Location 283369..284247 Replicon chromosome
Accession NZ_CP087169
Organism Pseudomonas sp. B21-047

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY26_RS01210 Protein ID WP_186661484.1
Coordinates 283369..283722 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY26_RS01215 Protein ID WP_186661486.1
Coordinates 283774..284247 (+) Length 158 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY26_RS01195 (LOY26_01195) 278625..280001 - 1377 WP_258714308.1 ATP-binding protein -
LOY26_RS01200 (LOY26_01200) 279994..280713 - 720 WP_186661480.1 response regulator transcription factor -
LOY26_RS01205 (LOY26_01205) 280854..283151 + 2298 WP_258714309.1 TonB-dependent siderophore receptor -
LOY26_RS01210 (LOY26_01210) 283369..283722 + 354 WP_186661484.1 type II toxin-antitoxin system HigB family toxin Toxin
LOY26_RS01215 (LOY26_01215) 283774..284247 + 474 WP_186661486.1 transcriptional regulator Antitoxin
LOY26_RS01220 (LOY26_01220) 284506..284712 - 207 WP_186661488.1 DUF3079 domain-containing protein -
LOY26_RS01225 (LOY26_01225) 284922..285392 + 471 WP_258714310.1 DUF2442 domain-containing protein -
LOY26_RS01230 (LOY26_01230) 285777..286652 - 876 WP_258714311.1 hypothetical protein -
LOY26_RS01235 (LOY26_01235) 286649..287302 - 654 WP_258714312.1 hypothetical protein -
LOY26_RS01240 (LOY26_01240) 287564..289036 + 1473 WP_186711463.1 dNTP triphosphohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(73-111)

Antitoxin

Antitoxin HigA

(43-154)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13754.86 Da        Isoelectric Point: 9.9559

>T224977 WP_186661484.1 NZ_CP087169:283369-283722 [Pseudomonas sp. B21-047]
MRVVTKTAVAQAIETYSQWKEPLNLWLTTFDRPPLRFESFDQIRDVWGTASGWNVDRIPHSKLRHTSKKGPLDIYVFDIK
KNECRIIAWINTRTGTIYMKDILPHAGYDKWCKSDVK

Download         Length: 354 bp

>T224977 NZ_CP120679:620918-621268 [Bacillus sp. HSf4]
TTGATTGTTAAACGCGGCGATGTTTATTTTGCTGATCTATCTCCTGTTGTTGGCTCAGAACAAGGCGGGGTGCGCCCGGT
TTTAGTGATACAAAACAACATCGGCAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CAAAATTACCTACCCACGTCGAAATTGATGCGAAACGCTATGGTTTTGAAAGAGATTCCGTTATATTGCTCGAACAGATT
CGGACGATTGATAAGCAAAGATTAACGGACAAAATCACTCATCTCGATGATGAAATGATGGAAAAAGTCAACGAAGCCTT
ACAAATCAGTTTGGCCCTTATCGATTTTTAA

Antitoxin


Download         Length: 158 a.a.        Molecular weight: 17323.53 Da        Isoelectric Point: 4.2969

>AT224977 WP_186661486.1 NZ_CP087169:283774-284247 [Pseudomonas sp. B21-047]
MKRDKIEANGLDSFIANISPMFDGLSDQIATMSKLLSACHDPIEDDDDLQGRMALIDELYAHADSEDHAAARFAELVADR
VYEYETETVLIPQSSQSEALAFLISDRGVKQKDLSGIATQSAVSEILNNKRKMTVGQIKGFADFFKVPVEFFMNGAV

Download         Length: 474 bp

>AT224977 NZ_CP120679:620632-620913 [Bacillus sp. HSf4]
TTGTCTGAATCCAGCGCAACAACTGAAATTATGATTCGCTTGCCAGAAGCTTTAGTATCGGAACTTGATGGTGTCGTCAT
GCAAGATAACGGGAGCAGAAATGAACTGATTTACCAAGCCACAAAAATGTATTTACGCGAGCGCAAAAATCGACAAATTC
GGGAATCGATGAGACGCGGTTATATGGAGATGGCAAAAATCAATTTGAACATCTCTTCCGAGGCACAATTTGCAGAGTAT
GAGGCTGAAAACACAGTAGAGCGCTTAGTAAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References