Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5264110..5264635 Replicon chromosome
Accession NZ_CP087166
Organism Pseudomonas sp. B21-051

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY52_RS23705 Protein ID WP_258676352.1
Coordinates 5264339..5264635 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY52_RS23700 Protein ID WP_258676350.1
Coordinates 5264110..5264349 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY52_RS23675 (LOY52_23645) 5259846..5260307 + 462 WP_258676346.1 GNAT family N-acetyltransferase -
LOY52_RS23680 (LOY52_23650) 5260589..5261239 + 651 WP_258676347.1 DedA family protein -
LOY52_RS23685 (LOY52_23655) 5261244..5262056 + 813 WP_258676348.1 zinc-dependent peptidase -
LOY52_RS23690 (LOY52_23660) 5262169..5262696 + 528 WP_003205933.1 inorganic diphosphatase -
LOY52_RS23695 (LOY52_23665) 5262920..5263666 + 747 WP_095139154.1 helix-turn-helix transcriptional regulator -
LOY52_RS23700 (LOY52_23670) 5264110..5264349 + 240 WP_258676350.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LOY52_RS23705 (LOY52_23675) 5264339..5264635 + 297 WP_258676352.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY52_RS23710 (LOY52_23680) 5265341..5265901 + 561 WP_258676354.1 hypothetical protein -
LOY52_RS23715 (LOY52_23685) 5265917..5266351 + 435 WP_027612917.1 hypothetical protein -
LOY52_RS23720 (LOY52_23690) 5266375..5267187 - 813 WP_258676356.1 DUF2135 domain-containing protein -
LOY52_RS23725 (LOY52_23695) 5267191..5268810 - 1620 WP_258676360.1 DUF2300 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11592.41 Da        Isoelectric Point: 8.4550

>T224961 WP_258676352.1 NZ_CP087166:5264339-5264635 [Pseudomonas sp. B21-051]
MTYSLEFDRRALKEWNKLGDTIRQQFKKKLSEVLENPRVEANRLRELPDCYKVKLKSAGYRLIYQVLDQEIVVFVVAIGK
REREAAYEAALDRLEPEC

Download         Length: 297 bp

>T224961 NZ_CP120654:c647993-647148 [Streptococcus agalactiae]
ATGAACAAAGCTAAATTAACAGCACTCTGTCATAAAATATCAAAGAATACTGGTTTAACCTTTAATTCCGTCATGACCTA
TTACTTCCTAGAAGTCATTTTGAAAAAATTAAGTCAAAGTTCTTATTCAAATCACTATATCTTCAAAGGAGGATTCCTAC
TTTCGAATGTCATCGGAGTTGAATCTCGTAGCACTGTTGATATTGACTTTTTATTCCATCAAATAACACTCTCAGAAGAA
ACTGTTAAACAGCAACTCAAGGAAATTTTAGCAGATTCCGAAGAAGGTATATCTTTTGTGATTCAATCAATCACAGCTAT
TAAAGAAAGTGATGACTATGGTGGCTATCGAGCAACAATTTCGTGCCAACTTGAGAATATTAAACAAGTTATCCATTTGG
ATATTGCGACAGGTGATGTTGTAACTCCTCAGCCGATTACATACGACTATAAAGCTATTTTTGATGAAGACAATTTTCCA
ATCATTGCTTATACAATTGAAACAATTCTAGCTGAAAAACTTCAAACCATCTATTCACGTAACTTCTTGAACAGTAGAAG
CAAAGATTTTTACGATGTTTATATTCTTTCCAAACTGAAGAAAGAAGACATTGACTTCATTCAGTTGAGAAATGCCTGTC
AGAGAACATTTTCATATCGCGAAACAGAACTCGATTTTGTAAAGATTATTGAACTACTCGAGAGGTTCAAATCTGACCCT
ATTCAGAATAAACAATGGCAAAATTATTCAAAAAAATATAGCTATACAAAAGGGATTTCACTTGCAGATGTTCTTGATGA
GATGATTCGTCTCATAACAGTTCTCATTTCTATAAATTCTGATTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8965.41 Da        Isoelectric Point: 6.3419

>AT224961 WP_258676350.1 NZ_CP087166:5264110-5264349 [Pseudomonas sp. B21-051]
MASINIRIDDELKKRSFAELEKLGVTPSELLRQTLQYVAERGKLPFKTALISQEDEALIAVVRERLASPQRIKVSLDDI

Download         Length: 240 bp

>AT224961 NZ_CP120654:c648580-647990 [Streptococcus agalactiae]
ATGTCAAAAAAAGAGATTCTACTCGATTTTATAGAAAAGAACAATGGAATTGTCACAAACAAAGATTGTAAAGCACTAGG
TATTCCAACAATATATCTGACAAGACTAGAGAAAGAAGGCATTATCTTCCGAGTTGAAAAAGGTATTTTCCTAACCCAAA
ACGGAGACTATGATGAATACTACTTCTTTCAATATCGTTTTCCTAAGGCTATTTTCTCTTATATTTCGGCACTGTATCTA
CAACAGTTTACAGATGAAATTCCACAATATTTTGATGTGACAGTTCCTAGAGGCTACCGCTTTAATACTCCTCCAGCTAA
TCTAAATATTCACTTTGTCTCTAAAGAATACAGCGAGCTGGGAATGACTACTGTACCTACTCCTTTGGGAAACAACGTAA
GGGTATATGATTTTGAACGTATTATTTGTGATTTTGTAATACATCGAGAAAAGATTGATTCCGAACTCTTTGTCAAGACA
CTTCAATCTTATGGGAACTATCCTAAAAAAAATCTAGCAAAACTCTATGAATATGCGACAAAAATGAATACTTTAGAAAA
AGTTAAACAAACTCTGGAGGTTCTAATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References