Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 478347..478936 Replicon chromosome
Accession NZ_CP087166
Organism Pseudomonas sp. B21-051

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LOY52_RS02095 Protein ID WP_258678000.1
Coordinates 478347..478652 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY52_RS02100 Protein ID WP_007943750.1
Coordinates 478649..478936 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY52_RS02075 (LOY52_02075) 474175..475242 + 1068 WP_007968321.1 uroporphyrinogen decarboxylase -
LOY52_RS02080 (LOY52_02080) 475420..476694 - 1275 WP_258677996.1 MFS transporter -
LOY52_RS02085 (LOY52_02085) 476813..477709 + 897 WP_258677997.1 LysR family transcriptional regulator -
LOY52_RS02090 (LOY52_02090) 477792..478229 - 438 WP_258677998.1 excinuclease -
LOY52_RS02095 (LOY52_02095) 478347..478652 + 306 WP_258678000.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY52_RS02100 (LOY52_02100) 478649..478936 + 288 WP_007943750.1 putative addiction module antidote protein Antitoxin
LOY52_RS02105 (LOY52_02105) 478993..479796 - 804 WP_007967258.1 hypothetical protein -
LOY52_RS02110 (LOY52_02110) 479822..481048 - 1227 WP_258678002.1 beta-ketoacyl-ACP synthase -
LOY52_RS02115 (LOY52_02115) 481048..481776 - 729 WP_258678004.1 3-oxoacyl-ACP reductase FabG -
LOY52_RS02120 (LOY52_02120) 481769..482233 - 465 WP_258678006.1 hotdog family protein -
LOY52_RS02125 (LOY52_02125) 482230..483426 - 1197 WP_258678008.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(3-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11512.17 Da        Isoelectric Point: 9.6535

>T224957 WP_258678000.1 NZ_CP087166:478347-478652 [Pseudomonas sp. B21-051]
MPEIIRSSTFSTWLLKLADNRARLRIQVRIDRMADGNFGDVKAVGEGLSEVRIDYGPGYRVYFMQQGRQVVILLCGGDKS
SQPRDIKQARLIAESWQEQNP

Download         Length: 306 bp

>T224957 NZ_CP120639:903766-904059 [Rhizobium sp. 32-5/1]
ATGAGTTTTAAGCTTTCTGTCGAGGCGGAAGAAGACATCATTGCGATCGCCGAGCAGGGTGCCCGTATGTTCGGAGTAAA
CCAGGCAAAACGCTACCACGATGAACTTTTCGCACTACTTGATCTGATAGCTGCTAACCCACGCATCGCACGCGAACGGA
ATGAGATCGAACCGCCCGTCAGAATTCATCCCTTCAAAGCACATCTCATCGTCTATCGGGTTGAAGACGATGAGAGAATT
TTCGTAGTGCGAATTCGCCACGGGCATGAAGACTGGGCAAGTATTTCAATGTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10372.72 Da        Isoelectric Point: 4.6412

>AT224957 WP_007943750.1 NZ_CP087166:478649-478936 [Pseudomonas sp. B21-051]
MTEQFTRWDSAEYLKTEEDMANYLDACMEEAGDDPAFIAKALGTIARARGMTQVARDAGLSRESLYRALSGEGNPEFGTI
LKVVKALGLKLHAST

Download         Length: 288 bp

>AT224957 NZ_CP120639:903527-903769 [Rhizobium sp. 32-5/1]
ATGGCGACAATGAACGTATCTCTTCCAGACCCTATGAAGGATTGGGTGGAGGCGCAGGCTAGGACTGGGCGATATTCGAA
CGCTAGCGACTACGTGCGCGACCTGATCAGACGCGATCAGACACGAAACGACAAGATTGCCGCCATGCAAAGTTTCGTAG
AGGCCGGGCTCCAAAGTGGCGTTGGCATTCGATCAAAGGATGAACTCTTTGCTGAGGCGATGGCTCGTGCCAGCAAGTCA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References