Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3794789..3795305 Replicon chromosome
Accession NZ_CP087165
Organism Pseudomonas sichuanensis strain B21-052

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY46_RS17795 Protein ID WP_125464711.1
Coordinates 3794789..3795070 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY46_RS17800 Protein ID WP_125464712.1
Coordinates 3795060..3795305 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY46_RS17770 (LOY46_17750) 3790097..3790453 + 357 WP_258704705.1 hypothetical protein -
LOY46_RS17775 (LOY46_17755) 3790389..3790889 + 501 WP_258704706.1 hypothetical protein -
LOY46_RS17780 (LOY46_17760) 3791026..3792387 + 1362 WP_125859318.1 hypothetical protein -
LOY46_RS17785 (LOY46_17765) 3792549..3793121 + 573 WP_258704707.1 hypothetical protein -
LOY46_RS17790 (LOY46_17770) 3793212..3794549 - 1338 WP_258704708.1 OprD family porin -
LOY46_RS17795 (LOY46_17775) 3794789..3795070 - 282 WP_125464711.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY46_RS17800 (LOY46_17780) 3795060..3795305 - 246 WP_125464712.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LOY46_RS17805 (LOY46_17785) 3795514..3795975 + 462 WP_258704709.1 PaaI family thioesterase -
LOY46_RS17810 (LOY46_17790) 3796096..3796419 + 324 WP_125464714.1 DUF2790 domain-containing protein -
LOY46_RS17815 (LOY46_17795) 3796430..3797158 - 729 WP_258704710.1 hypothetical protein -
LOY46_RS17820 (LOY46_17800) 3797276..3798022 - 747 WP_125464716.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-77)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10801.77 Da        Isoelectric Point: 10.9348

>T224952 WP_125464711.1 NZ_CP087165:c3795070-3794789 [Pseudomonas sichuanensis]
MTYKLEFLPSALKEWEKLGHTVREQAKKKLRERLVLPRVPADALRDLPNHYKIKLKSSGYRLVYRVEDQRVVVLVVAVGK
REGAAAYRSALKR

Download         Length: 282 bp

>T224952 NZ_CP120638:c1017257-1016856 [Rhizobium sp. 32-5/1]
GTGAAGGCGTTCTTTGACACGAATGTTCTCGTCTACCTCGTATCGGATGATCCGAAAAAGATACCTGCCGCCGCCTGTCT
GCGACAGGGCGGCATTGTCAGCGTTCAGGTATTAAACGAGTTCGTGCACGTCGTGCGCCGGAAACTGCGGCATGATTGGA
ACACGATCGAGTTGGCACTCAAGCACTTTCATATTGCGCTTGACGATATCGTCCCACTCACCGCCCAATTTCACGCCGCC
GCCCTGCCGCTCGCCCGCGATCATGGCCTCACCATCTACGATGCCCTCATCGTCGCAGCCGCCATCGAAGCTGGCTGCGA
CACGCTGTTCAGCGAAGACATGCAGCACGGCCGCGCCTTCGGTCGGGTGACCATCAGGAACCCGTTTCTGGAGACGGTGT
AG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8907.37 Da        Isoelectric Point: 4.6982

>AT224952 WP_125464712.1 NZ_CP087165:c3795305-3795060 [Pseudomonas sichuanensis]
MQNIFADITVSVSELKKNPTAVMAGAQGQPVAVLNHNRVMGYMVPAELYEAMMEQLEDIELAQLVKARAHEKGVPVKLDD
L

Download         Length: 246 bp

>AT224952 NZ_CP120638:c1017484-1017254 [Rhizobium sp. 32-5/1]
ATGCAAGTCTCGAAATGGGGCAACAGCCTGGCCGTACGACTGCCCAAGAAGCTTGTCGAGCAGATGGGTCTGGTCGAGGG
CGACGAGATCGATCTTGTGAACGGTGCCGGGAAGACGCTGATCATTAAAAAGGATGATCGTCGCGAGGCAGCCTTGGCCG
CGCTTGCGTCTCTCAATCTGCCGCTTCCTCCCGACTATAAATTCGACAGGGAAGAGGCCAATGAACGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References