Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1079958..1080604 Replicon chromosome
Accession NZ_CP087164
Organism Capillimicrobium parvum strain 0166_1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DSM104329_RS05340 Protein ID WP_259314359.1
Coordinates 1080188..1080604 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DSM104329_RS05335 Protein ID WP_259314358.1
Coordinates 1079958..1080179 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSM104329_RS05305 (DSM104329_01069) 1075248..1076195 - 948 WP_259314352.1 Ppx/GppA phosphatase family protein -
DSM104329_RS05310 (DSM104329_01070) 1076234..1076437 + 204 WP_259314353.1 hypothetical protein -
DSM104329_RS05315 (DSM104329_01071) 1076440..1077030 - 591 WP_259314354.1 TetR family transcriptional regulator -
DSM104329_RS05320 (DSM104329_01072) 1077099..1078205 + 1107 WP_259314355.1 multicopper oxidase domain-containing protein -
DSM104329_RS05325 (DSM104329_01073) 1078220..1079548 + 1329 WP_259314356.1 right-handed parallel beta-helix repeat-containing protein -
DSM104329_RS05330 (DSM104329_01074) 1079556..1079924 + 369 WP_259314357.1 plastocyanin/azurin family copper-binding protein -
DSM104329_RS05335 (DSM104329_01075) 1079958..1080179 + 222 WP_259314358.1 antitoxin Antitoxin
DSM104329_RS05340 (DSM104329_01076) 1080188..1080604 + 417 WP_259314359.1 PIN domain-containing protein Toxin
DSM104329_RS05350 (DSM104329_01078) 1080876..1084352 + 3477 WP_259314360.1 helicase-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14709.80 Da        Isoelectric Point: 7.1299

>T224949 WP_259314359.1 NZ_CP087164:1080188-1080604 [Capillimicrobium parvum]
VALLDVNALVALAWDSHVHHAAIRRWFATNAAAGWATCPVTESGFVRVSSNRRALPSAIGAEAARGVLAAMRTVEGHRFV
PDDVSVTDPDVPPLHGHRQVTDAHLLVLARRNDLRVVTFDAGLAALAEGRGVELLTVL

Download         Length: 417 bp

>T224949 NZ_CP120638:c402494-402213 [Rhizobium sp. 32-5/1]
ATGATCAAGGGCTTTCGCAACAAGGAAACAGAGATCCTTTTCCGGTCGAATGGACGGAGTCGTTTTCCGCCGGATATCGT
CCCGCGTGCTCGACGCAAGCTTCTGGTTCTGGATGCTGCTTTCAAGCTCGCCGATGTGACGGTTCCACCCAGTAACCGGT
TGGAACTGTTAAGCGGTAACCGACAAGGGCAGCATTCGATACGGATAAACGACCAATGGCGTATCTGCTTCGTCTGGGAC
AACGGCCATGCCCATGAGGTTGAAATTTGTGACTACCACTAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 7751.86 Da        Isoelectric Point: 4.7247

>AT224949 WP_259314358.1 NZ_CP087164:1079958-1080179 [Capillimicrobium parvum]
MRTTLDIDADVVAAARELAAAERRSLGSVISELARRGLSPARVESGGDLPVIRVPLGTAPITPEMVRRALDED

Download         Length: 222 bp

>AT224949 NZ_CP120638:c402203-401907 [Rhizobium sp. 32-5/1]
ATGCAATTCGTCATGGAAAACCCGATTCATCCCGGCGAAATTCTGAAGGAGGAGTTTCTGAAGGAGTATGCGTTGACGGC
CTATCGGGTCGCTGAAAGCATTGGTGTGCCGCGAACGCGCCTTGAGCGCATCCTGCGCGGTGAAAACGGCATCACTGCTG
ACACAGCATTGCGTCTTGCCCGCTATTTCGGAAACAGTCCCGAATTCTGGCTCAACCTGCAGCGAACCTATGATCTTGCT
CTTGCAGCAAAGAATGCCGGAGATTTGAACGCCATCGTCCCCGTGCAGGCCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References